Protein Info for MIT1002_03010 in Alteromonas macleodii MIT1002

Annotation: General secretion pathway protein F

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 transmembrane" amino acids 167 to 189 (23 residues), see Phobius details amino acids 217 to 236 (20 residues), see Phobius details amino acids 373 to 395 (23 residues), see Phobius details PF00482: T2SSF" amino acids 68 to 190 (123 residues), 115 bits, see alignment E=1.1e-37 amino acids 271 to 393 (123 residues), 109.9 bits, see alignment E=4.2e-36

Best Hits

Swiss-Prot: 60% identical to TAPC_AERHY: Type IV pilus assembly protein TapC (tapC) from Aeromonas hydrophila

KEGG orthology group: K02653, type IV pilus assembly protein PilC (inferred from 92% identity to amc:MADE_03232)

Predicted SEED Role

"Type IV fimbrial assembly protein PilC" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (401 amino acids)

>MIT1002_03010 General secretion pathway protein F (Alteromonas macleodii MIT1002)
MKATIVFEWQGKDRQGLSRKGEISAASLSEAKNLLRRQGISANRVKKPSKSLFRREKKIT
PADISVISRQIATMLAAGVTLIQSLEMISQGHANSSMRKLLGEITDEVKAGNPLSSALRK
HPLYFDDLYCDLVYTGEQSGALETIYDRIATYKEKAEALKSKIKKAMFYPIAVLVVAFIV
TTILLIFVVPQFEEIFSSFGAELPAFTQFVLAISRFVQDYGIFIAIGIGGAGFMFMRTYK
RSQKLRDTVDRNILKIPVIGEILKKASIARFTRTLATTFAAGVPLIGALESAAGASGNAV
YRDAILYMRKEVAGGMPMHVAMRATQVFPDMVTQMIAIGEESGAVDEMLSKIATIYEAEV
DDMVDGLTSLLEPMIMAVLGVVIGGLIVAMYLPIFQMGNVV