Protein Info for MIT1002_02963 in Alteromonas macleodii MIT1002

Annotation: Signal transduction histidine-protein kinase BarA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1055 transmembrane" amino acids 376 to 396 (21 residues), see Phobius details PF00512: HisKA" amino acids 418 to 483 (66 residues), 65.2 bits, see alignment 1.8e-21 PF02518: HATPase_c" amino acids 530 to 643 (114 residues), 102.8 bits, see alignment E=5.9e-33 PF00072: Response_reg" amino acids 663 to 779 (117 residues), 68 bits, see alignment E=3.3e-22 amino acids 806 to 915 (110 residues), 83.7 bits, see alignment E=4.2e-27 PF01627: Hpt" amino acids 972 to 1043 (72 residues), 26.6 bits, see alignment 2.3e-09

Best Hits

KEGG orthology group: None (inferred from 75% identity to amc:MADE_00899)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1055 amino acids)

>MIT1002_02963 Signal transduction histidine-protein kinase BarA (Alteromonas macleodii MIT1002)
MALPTFALLKEPLNTTSSVTTLDELKQRIQNNDESVETTFTELGYFFDAHPNAFQQARLF
NLRAYKHILEQDLVAGYETLLEARKLAKKGGNTMALAESFRLEGLILDLSGEHARALEAL
NKSLAAFIEVNSDNALLVYSAMGNVYMSLQNYEMMLQLGQNFLAAAQRLNDKENKAIAYF
FQGYAQTELGDYQDAKISLLLAEELFKEVHYPFIGIVHTKMAELHIAQGNLTEALTMLNR
AAESDRKVGFKYNEGSRLLRLVDIYIKRNQIDLAISELEGGLKKDAIKNDKSVVLSMLEK
LISLLESTNNFEAALEYSKLYTKTYEESFNEQQSRLLALNRVRLSISEKEETIKLLEKDN
QLKEQRNLIQKKQNTFQLYFIGFVILSLGLVVGLWLRTRQQRKALDALTQDLQKATKAKS
DFLARMSHEIRTPLNAIIGLTKLSQRAAEDKDQQTNLIQIEGASQTLLSIINDILDFSKI
EAGKLDIESTQFNLDALVNQTIRLHLGRAEEKHIELIQHISRDVPLNLIGDPLRIQQILS
NLVSNALKFTEDGLISVSVRCTHNVEDIQLEFEVKDTGIGLNSTQKALLFQPFNQGDESI
SRRYGGTGLGLAICKQLVTLMGGEIWVESQLGKGASFHFTVTVKQDASQQIVSPSKQLSL
LKVLIADDIGVSRDAIIESLSVANIKADVATGGKEAVAKMRAAVGNSAPYDVLILDWNMP
DIDGLEVAAIMKQEFSIKPPKVIMLYAFESPHMREQANQLGIRTFIKKPFSTSELVDKLQ
ELCLNVNTRTLPADAAPVPNLRGTKILFAEDNTLNQKVTLGLLNDTHANIEVVSNGFEAI
KALREDNSYDVVLMDIQMPVMDGLTAAKKIRDELKLTLPIIAMTAHAMQQDIDKSLAAGM
DGHINKPVDPNRFFDVLVEVLNKGKSTATTEVTGGPSANTIPLSFIDKSQAMQAMLNDET
LYKELLNDFAALNKELDNLRKAIDEKDYASIVRIAHIYITALRYIGAYALAELAATIELT
VKRNEHGSVAGFSDQLEALYTALVEMNAKVEGMVK