Protein Info for MIT1002_02885 in Alteromonas macleodii MIT1002

Annotation: Acyl-coenzyme A dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 749 transmembrane" amino acids 210 to 225 (16 residues), see Phobius details PF02771: Acyl-CoA_dh_N" amino acids 71 to 162 (92 residues), 53.7 bits, see alignment E=5.2e-18 PF02770: Acyl-CoA_dh_M" amino acids 167 to 267 (101 residues), 40.1 bits, see alignment E=6.8e-14 PF00441: Acyl-CoA_dh_1" amino acids 290 to 432 (143 residues), 51.2 bits, see alignment E=3.3e-17 PF09317: ACDH_C" amino acids 444 to 726 (283 residues), 242.8 bits, see alignment E=1.2e-75

Best Hits

KEGG orthology group: None (inferred from 98% identity to amc:MADE_02616)

Predicted SEED Role

"Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)" in subsystem Isoleucine degradation (EC 1.3.99.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.2

Use Curated BLAST to search for 1.3.99.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (749 amino acids)

>MIT1002_02885 Acyl-coenzyme A dehydrogenase (Alteromonas macleodii MIT1002)
MSIRTSLKKVLPPISITEQEALDAGDVWIESSIYQGKPDMQALRDIPQAKLSAEEQAFMD
GPVTELLNMIDDFELGNGKHIPQDVLDFLGKNRFFSMIIPKKFGGLEFSPYANSTIVATI
AAKSGAIAVTVMVPNSLGPGELLMHYGTTEQQDYWLPRLADGRDIPCFALTSPEAGSDAG
AIPDAAIVTKGEFNGEEVLGLRVSWDKRYITLAPIATVLGLAFKVFDPDQLLGDKLELGI
TCALLPKSHPGVELGNRHDPMGVRFYNGTTRGQDVFIPMDFIIGGQKNIGRGWQMLVSCL
GAGRGISLPAMGIATAQSAFKGTVEYSFVREQFGLPIGRFEGIQEKMADIAGKTFLLEAM
RVLTTEGLGLGVKPSVVTAIAKYHMTELGRDVMNSAMDIQAGKAIQRGPQNTLAGGYAAL
PIAITVEGANILTRNLMIFGQGAMRCHPYLKDMVDLIHSNESSADAEFNKVLRKTVGFSV
KNAFRSLGKGYLPFLRESESALPEVRKYEKRVNSISAKLAPLADLSLAVLGGDLKKAELL
SARLGDVMSYLYGAMAAIRFYEQRIEDRKLALPYFEYAMQWSLQQADQAIVNFINNFPNT
ATRGLMRLLTNTYTNSVAGISDDLVRELSIASMQDNSVKEQLTHLVRVTPGDGNDINEQA
FKAKHAVAHLLGKVQKALRKEPVVPFISFEHALNKLQEKGVVTADEAAKLHDYNEKRKLA
VRVDEYTFDMELVPASQTLKAIDGGQNAA