Protein Info for MIT1002_02761 in Alteromonas macleodii MIT1002

Annotation: Trigger factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 PF05697: Trigger_N" amino acids 1 to 144 (144 residues), 159.2 bits, see alignment E=1.3e-50 TIGR00115: trigger factor" amino acids 11 to 414 (404 residues), 489.2 bits, see alignment E=4.8e-151 PF00254: FKBP_C" amino acids 155 to 236 (82 residues), 65 bits, see alignment E=1e-21 PF05698: Trigger_C" amino acids 263 to 415 (153 residues), 138.9 bits, see alignment E=2.5e-44

Best Hits

Swiss-Prot: 78% identical to TIG_PSEA6: Trigger factor (tig) from Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)

KEGG orthology group: K03545, trigger factor (inferred from 93% identity to alt:ambt_04055)

MetaCyc: 58% identical to trigger factor (Escherichia coli K-12 substr. MG1655)
Peptidylprolyl isomerase. [EC: 5.2.1.8]

Predicted SEED Role

"Cell division trigger factor (EC 5.2.1.8)" in subsystem Bacterial Cell Division (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (434 amino acids)

>MIT1002_02761 Trigger factor (Alteromonas macleodii MIT1002)
MQVSVETTQGLERRLTITVPADTVDSAVKSRLQQLAKTQRINGFRPGKVPVNVIKKRFGQ
AVRQEVAGDVMQQNFYQAVIQEKIQPAGMPKFELTKDEDGQDLEFTASFEVYPEVEVKGV
SDIEIEKPVVEITDEDLDNMMETLQKQHATWKEVKRKAKKDDKVIIDFVGSIDGEEFEGG
KAEDFALELGKDRMIPGFEKPLVGAKAGEEVTIEVTFPEDYHAENLKGKDAVFQTTVKKV
EGLNLPKVDEEFAKLFGVEEGGVDALKAEVRKNMQRELNQTLKAQVKEDVIAKLVEANEI
DIPQALIDQEVNALREQAKQRFSQQGGGQNLPDLPAELFTDNAKRRVSIGLLLGEVIKQN
ELKADEAKVNEMIETAASAYEDPQEVVDYYNNNQELMQQMQNVALEEQAIEWVLEQAKVT
EVTKAFDEVMNKQA