Protein Info for MIT1002_02717 in Alteromonas macleodii MIT1002

Annotation: Sigma-E factor regulatory protein RseB precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF03888: MucB_RseB" amino acids 98 to 274 (177 residues), 172.5 bits, see alignment E=6.8e-55 PF17188: MucB_RseB_C" amino acids 292 to 386 (95 residues), 80.6 bits, see alignment E=8e-27

Best Hits

Predicted SEED Role

"Sigma factor RpoE negative regulatory protein RseB precursor" in subsystem Transcription initiation, bacterial sigma factors

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

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Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

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Find the best match in UniProt

Protein Sequence (394 amino acids)

>MIT1002_02717 Sigma-E factor regulatory protein RseB precursor (Alteromonas macleodii MIT1002)
MRCSSILALFFISGAAIQPLAAQTTSTSEEAKAPIAPVQNVNDGDVELDANSESNTRAGR
LDEADQEEAVREDVIQEQLEQSRSEQNASASRTREPQSANQWLAELQNIITNANFQVSFV
QTIAGKETVPYLWRHGIMEDGSELEQLNLQNGPGRELIRVNDVVSVFEPDVQPYSLRSKH
INGPIPSVLLYHPEQLAEAYEFVAVGRARVAGRSAQQIRIVSRDNTRFGYQLWLDESSGM
LLKLNMLDLQGALLEQIQVTAFAISPEPADYFSRINSASLPAPMALSNTPNRAHKWDVTY
LPAGMREIKQDTRRLALTGQIVEYKLFSDGLVDVSVYVQPAEDALGETLALRNEVSTFLT
LTDGKAQVTVVGEIPLQTANAIATSLRPVSSVSE