Protein Info for MIT1002_02701 in Alteromonas macleodii MIT1002

Annotation: Transcriptional repressor NrdR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 149 TIGR00244: transcriptional regulator NrdR" amino acids 1 to 147 (147 residues), 232.5 bits, see alignment E=9.3e-74 PF22811: Zn_ribbon_NrdR" amino acids 1 to 42 (42 residues), 69.7 bits, see alignment E=1.6e-23 PF03477: ATP-cone" amino acids 50 to 136 (87 residues), 84.3 bits, see alignment E=7.1e-28

Best Hits

Swiss-Prot: 100% identical to NRDR_ALTMD: Transcriptional repressor NrdR (nrdR1) from Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)

KEGG orthology group: K07738, transcriptional repressor NrdR (inferred from 100% identity to amc:MADE_02986)

Predicted SEED Role

"Ribonucleotide reductase transcriptional regulator NrdR" in subsystem Ribonucleotide reduction

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

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Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

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Protein Sequence (149 amino acids)

>MIT1002_02701 Transcriptional repressor NrdR (Alteromonas macleodii MIT1002)
MFCPFCSEQETKVIDSRLVAEGQQVRRRRECMVCHERFTTFESAELVMPRVIKRDGSREP
FNEDKLRAGLQRALEKRPVSTEKVEQCILSLKSQLRATGEREVSSELLGNLIMKALKELD
KVAYVRFASVYRSFEDIREFGEEIARLGD