Protein Info for MIT1002_02671 in Alteromonas macleodii MIT1002

Annotation: tetratricopeptide repeat protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 937 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details TIGR02917: putative PEP-CTERM system TPR-repeat lipoprotein" amino acids 15 to 918 (904 residues), 382.5 bits, see alignment E=1.9e-118 PF13432: TPR_16" amino acids 174 to 236 (63 residues), 23.9 bits, see alignment 4.5e-08 amino acids 208 to 270 (63 residues), 25.2 bits, see alignment 1.8e-08 amino acids 325 to 379 (55 residues), 19.3 bits, see alignment 1.2e-06 amino acids 695 to 749 (55 residues), 17.9 bits, see alignment 3.3e-06 amino acids 870 to 911 (42 residues), 17.3 bits, see alignment (E = 5e-06) PF14559: TPR_19" amino acids 213 to 271 (59 residues), 37.6 bits, see alignment 2e-12 amino acids 327 to 380 (54 residues), 25.4 bits, see alignment 1.3e-08 amino acids 870 to 916 (47 residues), 28.5 bits, see alignment 1.4e-09 PF13181: TPR_8" amino acids 482 to 513 (32 residues), 14.1 bits, see alignment (E = 3.9e-05) amino acids 722 to 751 (30 residues), 21.2 bits, see alignment (E = 2.1e-07) amino acids 893 to 919 (27 residues), 13.5 bits, see alignment (E = 6.1e-05)

Best Hits

KEGG orthology group: None (inferred from 93% identity to amc:MADE_01444)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (937 amino acids)

>MIT1002_02671 tetratricopeptide repeat protein (Alteromonas macleodii MIT1002)
MDFFNNKKRVVQRAIVSAVASSLIAFNSFASTSEDYEKALTAFNQNEYDEAYIHLKNSLQ
KDPENLAAKILMGEILLINGYLTAAEMEFVEALEMGADINLLAEPLGNTWLFLNRYQEIV
DFSDLSKLSGNAEREWLMIRATACIRLEDEQCALRDYNTIVSRTPDFVPAINGLASIALQ
NEDLSKATSLINKAMSLEPENAITWRLKGQLAYRQGDTDAATAHLQKALTFNRDDPIALR
NLVDLYLEAKDYDTAKLFVDEIIEDTPNDPLAILLNSWLQSRDNQQAIDNEKLKELNDFM
AQLDPELITSQPMLLYISGLTNFFNNNMETAAKDFNAYLQQEPDDLQAVLMLSQVYMATQ
QDKQALALLERHQDALMEDPDSALLLGDLFIRQNKAFKAERLLQNLEYKYPNENKLQLFK
IKLMAARGKQDEALSILENNLSTYKDNAGFLFTYSLMNLQAQQFKNALKGADLLSALFPN
EAEVFNLKAGILIRQGRLEEAKVNIEKALAQNPTLFPAKFNLAATESRLGNVDKSNLLVE
ELLALSPQHNETLMLKAFNLNKAGNLEEAKQIYLDILTLTPSNTGARERVSSLYQQQGDT
KNALYHLDLLIKDDFDNADYLLRKAALQLEAGQRADAEKTLSIVRNFINDDAGKLIAYAD
QARRVDNDENALDAMARAYEIANTSTFVTLRYVSLLLDMQNNDKAQSLLTTIPANQQQNP
VYYFLKGRLAANKGNSERAIKEFEKALDVDATFAQAFVAIYNYALNDQFVDVFLNTARKL
VSENENNLLAKNLLAQYLFFIQEFDESIALYKELVEQPNLLNPAEAYNRLAIMHIEESLV
TAKNYARQAYELQPNSAKILDTYGHIKALQGDYEGSLKMLRDAFARDANDPNIRYHLGYT
LAKLNRIEEAKKELEYAVNVERPFFKRPQARALLESL