Protein Info for MIT1002_02597 in Alteromonas macleodii MIT1002

Annotation: ferrous iron efflux protein F

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 40 to 64 (25 residues), see Phobius details amino acids 85 to 107 (23 residues), see Phobius details amino acids 115 to 135 (21 residues), see Phobius details amino acids 155 to 175 (21 residues), see Phobius details amino acids 187 to 207 (21 residues), see Phobius details TIGR01297: cation diffusion facilitator family transporter" amino acids 11 to 274 (264 residues), 83.7 bits, see alignment E=6.7e-28 PF01545: Cation_efflux" amino acids 14 to 212 (199 residues), 105.5 bits, see alignment E=1.6e-34

Best Hits

KEGG orthology group: None (inferred from 31% identity to cyn:Cyan7425_2240)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (306 amino acids)

>MIT1002_02597 ferrous iron efflux protein F (Alteromonas macleodii MIT1002)
MDIGFHHLEEKRLLTLSFYIAGAFVVIAFGFAILTSSGAILFDAAYSLIAFVMSMLTLKV
ANLVQRPDDDRFHFGYTAIEPTLNMFKSLIIIATCVYAVASSVQSLLAGGHAAEYGIGMV
YGVVATVGCFSISLYMRVKGKHLLSDLVKVDSHTWMIDGVLSASILFAFILAYALELTEY
RTLSPYVDPVLLIILGSAMLPVPFKILRESLNEVINKAPPEAISAVIEKKFKKTLADVPY
EHVEVRISKRGRDVYLLVHIIVDDAFSFATISELDEIRLKCEAEMREWDPAIIMDILFIK
DPELAE