Protein Info for MIT1002_02558 in Alteromonas macleodii MIT1002

Annotation: protease3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 917 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF00675: Peptidase_M16" amino acids 49 to 181 (133 residues), 58.1 bits, see alignment E=1e-19 amino acids 492 to 621 (130 residues), 65.4 bits, see alignment E=5.4e-22 PF05193: Peptidase_M16_C" amino acids 205 to 376 (172 residues), 98.3 bits, see alignment E=5.2e-32 amino acids 648 to 824 (177 residues), 89.5 bits, see alignment E=2.6e-29

Best Hits

KEGG orthology group: None (inferred from 94% identity to amc:MADE_01173)

Predicted SEED Role

"Zinc protease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (917 amino acids)

>MIT1002_02558 protease3 (Alteromonas macleodii MIT1002)
MTVLKHLTKRLKVSVGVLAVSSTLVGSAFAKNDINIDYEKFTTDNGLTVIVHEDRKAPVV
AVAVWYKVGSKDEPNGKSGFAHLFEHLMFNGTENYDDEWFGPLQEAGATGLNGTTNFDRT
NYFQTVPTPALDRILWMESDRMGHLLGAVTQEKLDEQRGVVQNEKRQGEDQPYGSVFTHI
FEGLFPIGHPYHHTVIGSMEDLNSASLDDVKGWFNQYYGPNNAILVLSGDINAEEAKPLV
NKYFADIEPGPALSKWEAWVPKRNANTREVIQDKVPQSRIYRLWVSPENTSSTATDLFIA
ASVMGDGKNSRLYKELVYDQQIATNASVFNYELQMASIFGVTVDVKDGVDVATVEKEIDK
VISEFLRKGPSKDEVKLVSTKRRASIIRGLEEVGGFGGKADTLASGEFIAGDPNYFKTEL
SELGQATPKGVKAAANKWLKEGWHQITVVPFIEHTASTEGVDRSSGLPSIDAETQLSFPE
VTETTLSNGVKVVFAKRSTVPLVNVAVQFDAGYAADAGGKLGLASFTTQMLDEGAGKYDA
LELAAELEQLGTDLNAGSNLDTTTVTMSMLTENMEPSLALMGDILKSPTFKEEEIERQRA
LILSNIAQQKTRPVSIALTLLPPLIYGEGHAYGIPFTGTGTEQDVQAITRDDLVNFKNTW
LRPDNATIFVVGDTTLGAIKPMLEKEFGKWKVEGSKGAKQIAEASMPEQGQAIIIDRPGA
QQSLILAAHLAPPTGADNNIAINAMNLTLGGAFTARVNMNLREDKSWSYGAYTFLQDARG
QRPFMVYAPVQTDKTGPSLLELKKELNAYLGEKPPMANELERARLDEVRSLPGQFETANA
VLYSLLSSERFNRQYSYPESLVEKYNSLSLDDLSNAAKEVLHPEKLAWIIIGDAEKIKAE
VEAAQLGPVSVQSMKSL