Protein Info for MIT1002_02473 in Alteromonas macleodii MIT1002

Annotation: putative HTH-type transcriptional regulator YxaF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 196 PF00440: TetR_N" amino acids 13 to 56 (44 residues), 26.4 bits, see alignment 7.3e-10 PF21993: TetR_C_13_2" amino acids 82 to 181 (100 residues), 84.5 bits, see alignment E=8.4e-28 PF16925: TetR_C_13" amino acids 83 to 182 (100 residues), 32.4 bits, see alignment E=1.6e-11

Best Hits

KEGG orthology group: None (inferred from 55% identity to shn:Shewana3_0685)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (196 amino acids)

>MIT1002_02473 putative HTH-type transcriptional regulator YxaF (Alteromonas macleodii MIT1002)
MSKSSAEGRQRVIETAASILSTRGLKGVSIREVAKLANAPLGSTYHHFPDGKVQIITEAI
EWAGEKAAERLKGCLDKDNRNGLQTFLHQWRERLHRSNFQQGCPIVAAAIEASQDEHEEQ
IKLAISRIFKRWQSILADHFISHGRTVVLSNSMALTVISCLEGAVILSRGYQTIEPFDAI
IDTLSLLVDQGKEDSE