Protein Info for MIT1002_02430 in Alteromonas macleodii MIT1002

Annotation: Altronate dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 496 PF08666: SAF" amino acids 14 to 81 (68 residues), 34.8 bits, see alignment E=3e-12 PF04295: GD_AH_second" amino acids 114 to 246 (133 residues), 153.5 bits, see alignment E=5.5e-49 PF20629: GD_AH_C" amino acids 256 to 495 (240 residues), 345.4 bits, see alignment E=2.3e-107

Best Hits

KEGG orthology group: K01685, altronate hydrolase [EC: 4.2.1.7] (inferred from 55% identity to scl:sce1245)

Predicted SEED Role

"Altronate dehydratase (EC 4.2.1.7)" (EC 4.2.1.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (496 amino acids)

>MIT1002_02430 Altronate dehydratase (Alteromonas macleodii MIT1002)
MDVKTQLVKVHNNDNVAVATCPIVAGTYIAEYDITASQDIPAGHKVALVSLSDGGDIVKY
GFSIGAATSQINAGEHVHSHNAKTKLKGTEQYVYAPSNTASKQNHLTSGLQFMGYRRENG
KVGIRNEVWIINTVGCVNRTADRIANECNRRFASECDGFRAFTHPFGCSQLGDDLDDTRT
ILASLASHPNAGAVLIVGLGCENNQLKNLLPHVDKPENRIRFYNAQEVVDELEEGVNAVY
DLLKVMANDKREPIDASELTLGMKCGGSDAFSGITANPTVGRVTDLMCNLGGSVILTETP
EMFGAEQLLMNRAKNKDVFEAFNSLIDEFKNYFIAHNQPIYENPSPGNKAGGLTTLEEKS
LGAVQKGGTSIIQSILQYGEPKQDKGLSLLQAPGNDAVSSTALAASGAHIVLFTTGRGTP
LGFPVPTVKISSNSDIANKKPHWIDFNAGQVLEGVSIDKCAEALLQHCLAVASGQQTCNE
KNGSHEIAIWKRGVTL