Protein Info for MIT1002_02392 in Alteromonas macleodii MIT1002

Annotation: Amino-acid carrier protein AlsT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 552 transmembrane" amino acids 18 to 36 (19 residues), see Phobius details amino acids 71 to 92 (22 residues), see Phobius details amino acids 97 to 116 (20 residues), see Phobius details amino acids 145 to 164 (20 residues), see Phobius details amino acids 184 to 203 (20 residues), see Phobius details amino acids 213 to 233 (21 residues), see Phobius details amino acids 243 to 266 (24 residues), see Phobius details amino acids 308 to 328 (21 residues), see Phobius details amino acids 435 to 450 (16 residues), see Phobius details amino acids 457 to 477 (21 residues), see Phobius details amino acids 489 to 507 (19 residues), see Phobius details amino acids 513 to 535 (23 residues), see Phobius details TIGR00835: amino acid carrier protein" amino acids 21 to 546 (526 residues), 593.1 bits, see alignment E=1.5e-182 PF01235: Na_Ala_symp" amino acids 57 to 551 (495 residues), 438.7 bits, see alignment E=1.4e-135

Best Hits

Swiss-Prot: 74% identical to DAGA_PSEHA: Na(+)-linked D-alanine glycine permease (dagA) from Pseudoalteromonas haloplanktis

KEGG orthology group: K03310, alanine or glycine:cation symporter, AGCS family (inferred from 97% identity to amc:MADE_01260)

Predicted SEED Role

"Na(+)-linked D-alanine glycine permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (552 amino acids)

>MIT1002_02392 Amino-acid carrier protein AlsT (Alteromonas macleodii MIT1002)
MEGLYGFLTMLDGFLGGAFWFPYVLLGVGLFFTIYLKFPQIRFFKHAWQVVTGKFDKESD
PGDTTHFRALTTALSGTVGTGNISGVAFAIFLGGPAALFWMWVTAFLGMTTKFVEVTLSH
KYRVKTEDGTMAGGPMYYMDRRLNMKWLAVAFAVATVVSSFGTGNLPQSNGIAQSIEATF
GFEPWIVGSVLGILLALVILGGIQRIAAFTARVVPVMAVIYLIGALAVIFANLDNIGPSF
SAVIGDAFTGSAAAGGFLGASLAYAFNRGVNRGLFSNEAGQGSAPIAHAAAKTKEPASEG
MVSLLEPFIDTILICTVTGLVILSSGVWKEKHENVFDRSDMYFVAGQYDDSNQDDVNKLY
GYLNEIEGNNVQPYTGSITVVNGTAVSDGFTLLNARSVAEDVKYAVGSEDLFTGTLKIVD
GKPVKENLEVSGKSLVHSAALTTIAFTRGFFGDFGQYIVSIGLMLFAFSTAIAWSYYGDR
AMTYLFGPRSVMPYRVIYVAGFVWAAFSDTTLVWALSAVAIVVMTLPNLFGIMLLCKEMK
ETVNDYWSRHKN