Protein Info for MIT1002_02305 in Alteromonas macleodii MIT1002

Annotation: putative integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 264 transmembrane" amino acids 48 to 67 (20 residues), see Phobius details amino acids 74 to 98 (25 residues), see Phobius details amino acids 121 to 141 (21 residues), see Phobius details amino acids 161 to 184 (24 residues), see Phobius details amino acids 196 to 211 (16 residues), see Phobius details amino acids 214 to 248 (35 residues), see Phobius details PF09955: DUF2189" amino acids 78 to 191 (114 residues), 90.8 bits, see alignment E=4.1e-30

Best Hits

KEGG orthology group: None (inferred from 95% identity to amc:MADE_01073)

Predicted SEED Role

"Putative cytochrome c oxidase, subunit I"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (264 amino acids)

>MIT1002_02305 putative integral membrane protein (Alteromonas macleodii MIT1002)
MSHHFKETPENAITQSGIARVIPCKELDVGDPVKWLSLALRDAMRAPGLTLFYGILFAVI
PWFIMYLVEMTGWHLVILPAIVCFMLVGPFLAAGLYDVSWEMEKGHKPTLRHSLRAMRRN
AFNEWGFAILLIVMMIFWLRVSSLIHALYPPYIENDLENLLPFLALGTIVGAGFTLAMLF
ITAFTQPILMERKVDLATAVLTSVNAVWLNKVPMLIWGAIIFTTVAIGYVTGFIGFIVLM
PIIGYASWHAYIDAIETKRERKYE