Protein Info for MIT1002_02275 in Alteromonas macleodii MIT1002

Annotation: 4-formylbenzenesulfonate dehydrogenase TsaC1/TsaC2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 255 PF00106: adh_short" amino acids 10 to 201 (192 residues), 194.1 bits, see alignment E=3.7e-61 PF08659: KR" amino acids 12 to 163 (152 residues), 41.8 bits, see alignment E=2.3e-14 PF01370: Epimerase" amino acids 12 to 178 (167 residues), 25.5 bits, see alignment E=1.7e-09 PF13561: adh_short_C2" amino acids 19 to 253 (235 residues), 223.9 bits, see alignment E=4.5e-70

Best Hits

Swiss-Prot: 38% identical to Y4LA_SINFN: Uncharacterized short-chain type dehydrogenase/reductase y4lA (NGR_a02730) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: None (inferred from 95% identity to amc:MADE_01006)

MetaCyc: 34% identical to 7alpha-hydroxysteroid dehydrogenase subunit (Bacteroides fragilis NCTC 9343)
7-alpha-hydroxysteroid dehydrogenase. [EC: 1.1.1.159]; 1.1.1.159 [EC: 1.1.1.159]

Predicted SEED Role

"Short-chain dehydrogenase/reductase SDR"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.159

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (255 amino acids)

>MIT1002_02275 4-formylbenzenesulfonate dehydrogenase TsaC1/TsaC2 (Alteromonas macleodii MIT1002)
MNVAANVEGKHILITGGGSGIGAASARVLSARGATVGIADLNEGNAKTLAEEIVAAGGKA
YAVAVDVTESAQVKAMFDTALSHNDKIDVIINNAGIDHFPAPLTEVDDAMFMKNIQVNLA
GVWYCMKNALKHMTATGGGHIINIASVAGLRSAPMISAYSASKHGVVGLTKSAAVEYARA
NIRINAVCPSFVDTPMVQGVLSKLDERGQKGLIGANPMKRLGKPEEIANAIAWLCSDESS
FMTGQSVVLDGGMLA