Protein Info for MIT1002_02217 in Alteromonas macleodii MIT1002

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 245 TIGR03420: DnaA regulatory inactivator Hda" amino acids 2 to 242 (241 residues), 212.8 bits, see alignment E=2.4e-67 PF00308: Bac_DnaA" amino acids 57 to 170 (114 residues), 25.4 bits, see alignment E=1.4e-09 PF22688: Hda_lid" amino acids 178 to 241 (64 residues), 64.6 bits, see alignment E=6.8e-22

Best Hits

KEGG orthology group: K10763, DnaA-homolog protein (inferred from 87% identity to amc:MADE_02146)

Predicted SEED Role

"Chromosomal replication initiator protein DnaA" in subsystem DNA-replication

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (245 amino acids)

>MIT1002_02217 hypothetical protein (Alteromonas macleodii MIT1002)
MQLPLLVTLPVDENFDSFVNTGNEEVVSVLKQIADALPHWREAPELGPLASLQLPLLTLL
GSTAIGKSHLLFATCHQLAEKSVSHLYLNLNNYEAWSLDIFEGLENLSLIALDNIHAIAG
DLRWEEALFDLLNRVIETKQTMVLCSSHLGPSNPAFVLPDLRSRLAWGVIYHVNQLDDNG
REEAVRLRAAERGLKLSNQALQFLLHHSERDLKSLMSLLARLDTRSLQEQKRLSVGMVKR
ELNLS