Protein Info for MIT1002_02204 in Alteromonas macleodii MIT1002

Annotation: putative inner membrane transporter yiJE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 291 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 37 to 55 (19 residues), see Phobius details amino acids 76 to 96 (21 residues), see Phobius details amino acids 102 to 122 (21 residues), see Phobius details amino acids 129 to 148 (20 residues), see Phobius details amino acids 154 to 173 (20 residues), see Phobius details amino acids 186 to 210 (25 residues), see Phobius details amino acids 217 to 237 (21 residues), see Phobius details amino acids 247 to 266 (20 residues), see Phobius details amino acids 272 to 289 (18 residues), see Phobius details PF00892: EamA" amino acids 5 to 145 (141 residues), 40.6 bits, see alignment E=1.4e-14 amino acids 159 to 289 (131 residues), 60.9 bits, see alignment E=7.4e-21

Best Hits

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (291 amino acids)

>MIT1002_02204 putative inner membrane transporter yiJE (Alteromonas macleodii MIT1002)
MLKTFVLVAIAMIAFAANSLLCRMALANTDIDPASFTILRLASGAIALLLLSSYFQRRKS
ESVPSQGLFHGLKTNASVLGGISLFVYAICFSYAYISMSTGTGALLLFGAVQLTMISVGL
FNGERFKKWQWLGFVLAFLGLVILLLPSAAAPPLLAGAVMVLAGMAWGVYSLLGKKSSSA
LLSTSGNFVYAAFFCVPLVGAVCFVGADNFVLDSEGVYYALASGVFASGCGYAIWYSALP
LIKSTTAATVQLSVPVIASLMGWLALGEPLTMQILVASIATLGGIYLVIKK