Protein Info for MIT1002_02033 in Alteromonas macleodii MIT1002

Annotation: efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 772 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 225 to 243 (19 residues), see Phobius details amino acids 251 to 274 (24 residues), see Phobius details amino acids 280 to 301 (22 residues), see Phobius details amino acids 322 to 345 (24 residues), see Phobius details amino acids 353 to 377 (25 residues), see Phobius details amino acids 410 to 428 (19 residues), see Phobius details amino acids 614 to 630 (17 residues), see Phobius details amino acids 637 to 659 (23 residues), see Phobius details amino acids 665 to 684 (20 residues), see Phobius details amino acids 711 to 731 (21 residues), see Phobius details amino acids 739 to 763 (25 residues), see Phobius details PF03176: MMPL" amino acids 145 to 411 (267 residues), 40.1 bits, see alignment E=2.2e-14 amino acids 469 to 761 (293 residues), 58.3 bits, see alignment E=6.6e-20 PF02460: Patched" amino acids 157 to 305 (149 residues), 29.6 bits, see alignment E=2.2e-11

Best Hits

KEGG orthology group: K07003, (no description) (inferred from 94% identity to alt:ambt_08065)

Predicted SEED Role

"FIG005548: transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (772 amino acids)

>MIT1002_02033 efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family (Alteromonas macleodii MIT1002)
MTHFLEKLVFGNRKIVVALFAIATVFLGYQASQMRLDAGFEKNIPLNHEYMKTYIEHRQD
FGGANNILVSVCDKNDNIYNQNFFDTLKNVHDQLFFINGVNRSLVISLFSPSTRFTEIVE
GGFAGGPVIPADFNSASPEALELVAANVEKANIVGRQVSSDYSCAMVTAQLLDIDPQTGE
PLNTLALAAELEEQLRGQYENENTSIHIIGFAKMIGDVADGAKDVLIFFAIAIAITAVMV
YFFSRSIMLTLLPLVCSIIAVIWQLGLLTSIGFGMDPMSILVPFLVFAIGVSHGVQMINA
VEKQAVTGIGAKRASMAAFRNLLVPGGIALLSDTVGFMTLLVIDIGIIRELAITASMGVA
VIILTNLLLLPVLMSFLKLDQKYVEKFAGKENANSKFWEVIAACSRKKPAAIILIVTAIL
FVFGHFQAQNMKIGDLHAGAPALHETSRYNQDTFLITDKYEVTVDYISILVETTPEACTS
HSVMKAMDDFQWKMENVQGVQSAVSLASVAKIVNAGYNEGNVKWQVIPRNQQTLVQAISR
VPTSSGLLNGDCSVMPIILFMEDHKAETISRVVDAVKSYRAEYQSDDMKFSLASGPVGVM
AATNEAVSAAQDPMMLYVFGAVIALCLISFRSLRATLVVVIPLYVVSVLAQALMTYLQIG
LTVSTLPVIALGVGIGVDYGIYILSTKSLMLKKGATVQEAYFAALKERGSAVLFTGITLA
IGVSTWVFSSLKFQMDMGILLTFMFVVNMLGAIIVLPALARFLWWNKNDPNA