Protein Info for MIT1002_02028 in Alteromonas macleodii MIT1002

Annotation: Aminopeptidase N

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 869 TIGR02414: aminopeptidase N" amino acids 10 to 864 (855 residues), 1133.7 bits, see alignment E=0 PF17900: Peptidase_M1_N" amino acids 23 to 185 (163 residues), 49.4 bits, see alignment E=1.2e-16 PF01433: Peptidase_M1" amino acids 224 to 437 (214 residues), 202.3 bits, see alignment E=1.6e-63 PF11940: DUF3458" amino acids 443 to 545 (103 residues), 53.7 bits, see alignment E=4.5e-18 PF17432: DUF3458_C" amino acids 550 to 865 (316 residues), 341.2 bits, see alignment E=1.5e-105

Best Hits

KEGG orthology group: K01256, aminopeptidase N [EC: 3.4.11.2] (inferred from 88% identity to amc:MADE_02005)

Predicted SEED Role

"Membrane alanine aminopeptidase N (EC 3.4.11.2)" (EC 3.4.11.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.2

Use Curated BLAST to search for 3.4.11.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (869 amino acids)

>MIT1002_02028 Aminopeptidase N (Alteromonas macleodii MIT1002)
MSVQAKRRADYQPPAFSIATVDLHITLHPTQTKVISTLSVTRNGAHDSPLVLDGDNLSLD
SISINGTHLSDNEYTVTDSALSVVTELDEFVLEITNTIAPEHNKALEGLYLSGGAYCTQC
EAEGFRRITYFMDRPDVLSVYTVTVVADKSVPMLLANGNPVDKGEVDENTHFVKWHDPHP
KPCYLFALVAGDFDLLTDSYTTTSGKEVALELYVDKGKKSQGIFALESLKRAMKWDEDVF
GLEYDLDIYMIVAVDFFNMGAMENKGLNVFNSKFVLADQKSATDDDFFNVESVIAHEYFH
NWTGNRVTCRDWFQLSLKEGLTVFRDQQFSADMTSALSNRIKHVRVMREHQFAEDASAMS
HPIRPEEVIEMNNFYTVTVYDKGAEVIRMFHTLLGPDGFRRGMDEYFRRHDGQAVTCDDF
ISAMQSATDLDLTQFTRWYSQSGTPVISVAHSTEVDDDGIVKHSFTLSQHTPATSDQKEK
LPLYIPVNIEIIDDEGKSYTDNESLIQNGMVILKDDAMRFTVEAKTTNLTPVVLGNFSAP
AKVENPLGTESLLTIFKHAKDPFNRWDAMQTLYDRCVKQLEESPGSGISNEIWNGIKQAI
AQEQNNLELLSECLVIPSFETLCQSRSNINVSALSKARKAFCDQFARALEKELKHVFENI
EKSAYRYTQEAVNQRRCKNVVLAHLARLPQHEHIVVSQFETADNMTDTLGALRSAPHCSA
TTFDSLMAQFEESWNHDPLVLDKWFALHATQNRDDIFATITMLCEHPQFAMSNPNRVRSV
IGSFAFYNSERFHALDGSGYKFVTDYLLKLDAVNPQVAARIVTPLTQWQGFASEHQVHMK
QQLGRLLNHKGLSKDLFEKVSKSLAYDKH