Protein Info for MIT1002_02010 in Alteromonas macleodii MIT1002

Annotation: DNA recombination protein RmuC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details PF02646: RmuC" amino acids 120 to 416 (297 residues), 356.4 bits, see alignment E=5.4e-111

Best Hits

Swiss-Prot: 52% identical to RMUC_YERPE: DNA recombination protein RmuC homolog (rmuC) from Yersinia pestis

KEGG orthology group: K09760, DNA recombination protein RmuC (inferred from 90% identity to amc:MADE_01951)

Predicted SEED Role

"DNA recombination protein RmuC" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (429 amino acids)

>MIT1002_02010 DNA recombination protein RmuC (Alteromonas macleodii MIT1002)
MLINLISSEPISFLIAFVSVCAFSLYSFIRGQANATKIAQLSQINEQLQNDLNSERIAIA
KLQAQNEAHQARIQALHAAHEDKLASMNASEQRLHTQFENLANRIFEEKQQRYTQQTKHN
IEAVLAPFKNELDGFKRQISEQHIREGQERASLKTEILSLKALNQKITEEAAALTNALKG
DNKKQGNWGEVVLERILKESGLREGHEFETQMSATSEHGKRFQPDVVVHLPNDKDVIIDS
KVSLAAYERYYNCDDEAEKAQFLSQHVASIKGHIKGLGAKDYQTLKGIKTLDYVLLFIPI
EPAFLIAVEEEPDLVTMALNHNIMLVSPTNLLVALRTINNIWQYEYQNQNAQLIAEQAAK
LYDKFVGFVTDMEKVGKSMDIAHANYEQAMNKLTSGRGNLVRQIEKFRELGVQPSKRMSQ
HLQQLSQDD