Protein Info for MIT1002_01995 in Alteromonas macleodii MIT1002

Annotation: putative rhodanese-related sulfurtransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 331 PF17773: UPF0176_N" amino acids 4 to 95 (92 residues), 100.1 bits, see alignment E=7.4e-33 PF00581: Rhodanese" amino acids 116 to 209 (94 residues), 38.9 bits, see alignment E=1e-13

Best Hits

Swiss-Prot: 71% identical to Y3316_ALISL: UPF0176 protein VSAL_II0216 (VSAL_II0216) from Aliivibrio salmonicida (strain LFI1238)

KEGG orthology group: K07146, UPF0176 protein (inferred from 95% identity to amc:MADE_01937)

Predicted SEED Role

"Rhodanese domain protein UPF0176"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (331 amino acids)

>MIT1002_01995 putative rhodanese-related sulfurtransferase (Alteromonas macleodii MIT1002)
MSKYIVCAMYKFVALENFKEIRHPLLETMEANGIKGTLLLAHEGINGTVSGTREGIDALL
AYLNSDERINPISCKESLHDEQPFYRTKVKLKKEIVTMGVEGIDPRKTVGTYVKPKDWNA
LISDPDVTVIDTRNGYEIEIGTFKHAIDPKTETFREFPEYVAKELDPSKNKKVAMFCTGG
IRCEKSTAYLKEQGFDEVYHLEGGILQYLEDVPKEESLWEGDCFVFDNRVAVNHDLEKSH
YEQCYACRLPITEEDKQSDKYEPGVSCPHCFGTHTDDQIARFREREKQVQLAKERQQEHV
GTEARLTMEQKRQEKAEAQRLRALKAKENQA