Protein Info for MIT1002_01883 in Alteromonas macleodii MIT1002

Annotation: Proline permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 504 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 45 to 68 (24 residues), see Phobius details amino acids 74 to 92 (19 residues), see Phobius details amino acids 124 to 147 (24 residues), see Phobius details amino acids 160 to 181 (22 residues), see Phobius details amino acids 187 to 206 (20 residues), see Phobius details amino acids 231 to 253 (23 residues), see Phobius details amino acids 275 to 295 (21 residues), see Phobius details amino acids 308 to 334 (27 residues), see Phobius details amino acids 374 to 391 (18 residues), see Phobius details amino acids 397 to 420 (24 residues), see Phobius details amino acids 429 to 447 (19 residues), see Phobius details amino acids 459 to 477 (19 residues), see Phobius details TIGR02121: sodium/proline symporter" amino acids 6 to 498 (493 residues), 651.3 bits, see alignment E=9.4e-200 TIGR00813: transporter, solute:sodium symporter (SSS) family" amino acids 34 to 437 (404 residues), 283.5 bits, see alignment E=3.2e-88 PF00474: SSF" amino acids 34 to 437 (404 residues), 302.7 bits, see alignment E=2.1e-94

Best Hits

KEGG orthology group: K03307, solute:Na+ symporter, SSS family (inferred from 96% identity to amc:MADE_01675)

Predicted SEED Role

"Proline/sodium symporter PutP (TC 2.A.21.2.1) @ Propionate/sodium symporter" (TC 2.A.21.2.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (504 amino acids)

>MIT1002_01883 Proline permease (Alteromonas macleodii MIT1002)
MPMESYLSLAVYFIAMLGIGLFAYRQSTSDISGYILGGRQVSPQVTALSAGASDMSGWML
MGLPGAMYLTGFDAVYIAIGLVAGALANYLLVAPKLRVYTEVANDSLTVPEFFAKRFDTP
NSSLRIVSAVIIVLFFTLYTSAGLVAGGKLFESAFSVDYQLGLFITLGVVVSYTLLGGFL
AVSLTDFVQGCIMFVALVLVPIVAFTEFDSVSQMTSAAYQSVPNFSESLETLTIVGLLSS
LGWGLGYFGQPHIIVRFMAIRSVNAIGTARNIGMSWMLVTIIGALATGFVGIAYANQFGL
AVDDPETIFIIFSQLLFHPLISGFLMAAILAAIMSTISSQLLVSASSLTEDIYRVMVNKK
SSTKALSEKQTVTIGRYGVAGVALVALLLAMDASNTILSLVSNAWAGFGAAFGPLVLFCL
YKKDLTAKAAMAGMISGAVTVLFWIYAPVLADGKTLSSVIYEIIPGFAVSMLTLYVVSRF
SENPSSNVQATFARASEELANQQS