Protein Info for MIT1002_01767 in Alteromonas macleodii MIT1002

Annotation: Sensory/regulatory protein RpfC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1111 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 56 to 78 (23 residues), see Phobius details amino acids 91 to 111 (21 residues), see Phobius details amino acids 118 to 138 (21 residues), see Phobius details amino acids 154 to 175 (22 residues), see Phobius details amino acids 191 to 210 (20 residues), see Phobius details amino acids 230 to 256 (27 residues), see Phobius details PF03707: MHYT" amino acids 66 to 122 (57 residues), 66.5 bits, see alignment 8.8e-22 amino acids 129 to 175 (47 residues), 46.8 bits, see alignment (E = 1.2e-15) amino acids 199 to 248 (50 residues), 25.9 bits, see alignment (E = 4.1e-09) TIGR00229: PAS domain S-box protein" amino acids 267 to 393 (127 residues), 75.5 bits, see alignment E=2e-25 amino acids 394 to 521 (128 residues), 40.3 bits, see alignment E=1.6e-14 PF00989: PAS" amino acids 274 to 363 (90 residues), 29.3 bits, see alignment E=3.6e-10 PF13426: PAS_9" amino acids 281 to 380 (100 residues), 39.4 bits, see alignment E=3.1e-13 amino acids 421 to 512 (92 residues), 27.4 bits, see alignment E=1.7e-09 PF08447: PAS_3" amino acids 423 to 507 (85 residues), 49.7 bits, see alignment 1.9e-16 PF00512: HisKA" amino acids 534 to 599 (66 residues), 69.5 bits, see alignment 1e-22 PF02518: HATPase_c" amino acids 647 to 756 (110 residues), 112.5 bits, see alignment E=7.3e-36 PF00072: Response_reg" amino acids 781 to 895 (115 residues), 86.1 bits, see alignment E=9.5e-28 PF01627: Hpt" amino acids 948 to 1024 (77 residues), 30.6 bits, see alignment 1.6e-10

Best Hits

KEGG orthology group: None (inferred from 82% identity to amc:MADE_01755)

Predicted SEED Role

"Related to two-component system sensory/regulatory protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1111 amino acids)

>MIT1002_01767 Sensory/regulatory protein RpfC (Alteromonas macleodii MIT1002)
MISRFFTFEEHATLIEGAYHVPLVILSLMVAVFASYMAFNVAGQAAITEHKLRPNTLLGT
GSVALGGGIWSMHFLGMTAFDLCLPVDYDPLITGLSAVPGFAAAWVALHLLTKSRISLAE
IMIGGVLVGAGIGTMHYSGMAAMEMAPLLRYDLGMFALSIVVAVCLAMLSLWIKFGITAA
TKSKKLLGKHVLLASIVMGLAISGMHYTGMAAARFVLPPGMETSNQSSDIAVFLAISIAI
VTLVLITTVLGISLLFKYRDVMVRAIESERIQSAITDTAVDAILTVDEKGIIKTANPSVE
RIYGYTQQEIIGMHASEIITPERRHLFGDDFFSQRVVPTVQIIGTGREVEVLRKDGERIP
VRLGVGYTKIDGKPVFVSFASDLRKRKEMEDALRESEAKFRSLISNIPGMAYRCLSMPGW
PMVFISDAVIEVTGYPPEDFILPNPKRSFADLYHPSDVERLSSISPDEGAFSYEYRIVAK
SGEVKWVIEHGVQVKDDDGMVLYVDGFISDITHRKVMENELKAAKENAEQAAAARTAFLA
NMSHEIRTPMNAIIGFSDLMLGEALREEQKSHLTTINRSARSLLHLLNDILDSAKLDKGK
LDLDYRDFLIREELDLVISTFWLEAKRKKVGLVLNVDDSVANGYRGVPERMRQVLNNLIG
NAVKFTHEGEVTINVKSDEKYVYFDVTDTGIGMTQEQVERVFDPFSQADASMSRKYGGTG
LGTTISKQLVELMGGNICATSEKGKGTTFTFRLPLEVVEIDDYVSSELSSKAVRIETSLT
VLIVDDVQQNLELLSLLLKRAGHSVETATDGQIALDKMRAKSFDVVLMDLQMPKLDGLEA
AKKRREFEKENSLPPTPIIALTASVLVQDKHAAQQAGMEGFANKPVDFPQLMDEIARVLN
IDTLQVDSVPDTLEVNAPASALKVDKNVLDLKKAVDLWGSEEAVLQEVDKFSTTCRDKVD
DLMGAAIREDYKAVAALSHGLKGTSGNLCLTTFYHTTREIEAQALKSEVNIEDVNRLRDA
LDKIELMLGKSPLYAENAINESIDNALLLSHLEAMLDSVEQNMVDEDELSFLREVGCSSH
KEQITQILLDIDDFEFELAHERISTLIQELK