Protein Info for MIT1002_01704 in Alteromonas macleodii MIT1002

Annotation: N-succinylarginine dihydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF04996: AstB
  • amino acids 3 to 444 (442 residues), 743.1 bits, E=5e-228
• TIGR03241: succinylarginine dihydrolase
  • amino acids 4 to 444 (441 residues), 743.4 bits, E=4.9e-228

Best Hits

Swiss-Prot: 78% identical to ASTB_PSEA6: N-succinylarginine dihydrolase (astB) from Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)

KEGG orthology group: K01484, succinylarginine dihydrolase [EC: 3.5.3.23] (inferred from 96% identity to amc:MADE_02354)

MetaCyc: 55% identical to N-succinylarginine dihydrolase (Escherichia coli K-12 substr. MG1655)
N-succinylarginine dihydrolase. [EC: 3.5.3.23]

Predicted SEED Role

"Succinylarginine dihydrolase (EC 3.5.3.23)" in subsystem Arginine and Ornithine Degradation (EC 3.5.3.23)

MetaCyc Pathways

• L-arginine degradation II (AST pathway) (5/5 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.23

Protein Sequence (446 amino acids)

>MIT1002_01704 N-succinylarginine dihydrolase (Alteromonas macleodii MIT1002)
MKQFEVNFDGLVGPTHNYAGLSFGNVASLNNANAKSSPKQAAKQGLAKAKALADMGMIQG
VLAPQERPDIAALRRLGFTGSDARVLESAAKQSREIFLACCSASSMWTANAATVSPSADT
ADGRVHFTPANLTNKFHRSLEPQVTGNILRGTFANEKHFAHHQHLPDNEHFGDEGAANHT
RLCSNYGQAGVELFVYGRHAFDTSKPAPKKYPARQTLEACQAVARLHGLDDDGVVYMQQN
PDVIDQGVFHNDVIAVGNQNVLFFHEQAFHQKDAGFKELQAKFGSEPLHFIEVPTAEVSV
QDAVKTYLFNTQIITLPGGDMTIIAPTECEENEAVKRYLDKLVTLGTPIKSVNYFDVKQS
MRNGGGPACLRLRVAMNDQELAAVNQNTLINDTQFARLNAWVDKHYRDELGEDDLRDPQL
LIESRTALDELTQLLKIGSVYPFQQA