Protein Info for MIT1002_01702 in Alteromonas macleodii MIT1002

Annotation: Glutamate-aspartate carrier protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 38 to 58 (21 residues), see Phobius details amino acids 63 to 83 (21 residues), see Phobius details amino acids 102 to 123 (22 residues), see Phobius details amino acids 164 to 183 (20 residues), see Phobius details amino acids 201 to 221 (21 residues), see Phobius details amino acids 237 to 258 (22 residues), see Phobius details amino acids 276 to 294 (19 residues), see Phobius details amino acids 317 to 340 (24 residues), see Phobius details amino acids 347 to 375 (29 residues), see Phobius details PF00375: SDF" amino acids 10 to 417 (408 residues), 430.7 bits, see alignment E=2.8e-133

Best Hits

Swiss-Prot: 34% identical to DCTA_RHILW: C4-dicarboxylate transport protein (dctA) from Rhizobium leguminosarum bv. trifolii (strain WSM2304)

KEGG orthology group: None (inferred from 98% identity to amc:MADE_02356)

Predicted SEED Role

"Proton/glutamate symport protein @ Sodium/glutamate symport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (448 amino acids)

>MIT1002_01702 Glutamate-aspartate carrier protein (Alteromonas macleodii MIT1002)
MSSSAHKYSLTARIFIGMAAGILTGVFLQLLFDDSGDFTFSIFGLAFSTYNILVEGIFST
LGQIFIASLKMLVVPLVFVSLICGTSTLSDPSKLGRLGAKSVGLYVVTTAIAITLAMSIA
LVVSPGDGLNLTTETTFQAKEAPSLSDVIVNMFPSNPINSMAQGNMLQIIVFAVLFGIAM
AMTGDAGKRLTAIFEDINTVIMRLVTIIMNLAPYGVYVLMAKLFSTIGGETILSLAKYFF
LVFGVLILHGLVTYSVLLKALSGLNPVILMKKMRDAALFAFSTSSSSATLPVTMETAKNK
LGVGNSVSSFTLPLGATINMDGTAIMQGVATVFIAQVYAVDLSLGDYMMVVLTATLASIG
TAGVPGVGLIMLAMVLQQVNLPVEGIALIIGVDRLLDMTRTAVNITGDCMVSCIVAKSEG
ALDESVYNDPKAGLKQEDVDFEHFEKNK