Protein Info for MIT1002_01682 in Alteromonas macleodii MIT1002

Annotation: Putative diguanylate cyclase YeaJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 315 transmembrane" amino acids 27 to 47 (21 residues), see Phobius details amino acids 55 to 79 (25 residues), see Phobius details amino acids 86 to 105 (20 residues), see Phobius details amino acids 118 to 141 (24 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 164 to 282 (119 residues), 73.2 bits, see alignment E=1e-24 PF00990: GGDEF" amino acids 165 to 290 (126 residues), 82.8 bits, see alignment E=1.3e-27

Best Hits

KEGG orthology group: None (inferred from 79% identity to amc:MADE_02397)

Predicted SEED Role

"FIG160596: Signaling protein with membrane-bound sensor domain and GGDEF domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (315 amino acids)

>MIT1002_01682 Putative diguanylate cyclase YeaJ (Alteromonas macleodii MIT1002)
MYPIQEISKESTMFTFTNSTQFRHHKLWLAFTFCVVALAVCLAFIFGDAKESTVISGLDI
VGEGSIAFLTLAWMLAALASRPPGKVTSLLTVGLGFFLFSVSLDFLDEFFHYPEEAYWLS
MIESYPAAVGMVVMTAALYQWHLEQRALNLQLRRREWDFRDHDAIDPITQLYRAEYWKTQ
INKLQQSGKSAVIAIIDINNFSLFNQKHGYTEGDRYLQDIAQLVIMNLRQQDLACRYAGD
RFAILIPDVSPMQADVILNDIKVSIQHLAFRHSLNANAIYTTARSTQVTLLPNQRLATVL
NTMLLELERAHDSAA