Protein Info for MIT1002_01626 in Alteromonas macleodii MIT1002

Annotation: GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 409 transmembrane" amino acids 76 to 96 (21 residues), see Phobius details PF00534: Glycos_transf_1" amino acids 223 to 382 (160 residues), 102 bits, see alignment E=5.5e-33 PF13692: Glyco_trans_1_4" amino acids 230 to 372 (143 residues), 80.1 bits, see alignment E=4e-26

Best Hits

Predicted SEED Role

"Colanic acid biosynthesis glycosyl transferase WcaL" in subsystem Colanic acid biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (409 amino acids)

>MIT1002_01626 GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase (Alteromonas macleodii MIT1002)
MSGTKQVCFFIRSFPVLSQTFVLNQVKDLVAEGVDVHVLAVNPIKNDNDVVAEVFGTRAQ
ANVTSILPSEHDKISYLYMLFGFLYCLCSPKRFRLIKLFFYFLIRRNKFLAKDLMCIVWF
LKSRDIKIDNCVAHFGSNGVIFDYLVKAELIECDNLFTIFHGYEISRYDQLTIWEKLYGK
LGGKLLPISEHWKSKLVSLGVAPSRIEVVHMGVDVDRFSYNEKAASTPLSILSVARATEK
KGLHFAIEAVLMCPIECSYTIIGDGVLLPELRNKANNHPNGHRVIFKGAQPSSVVASSLK
STDLFLLPSVRDSSGDMEGIPVSLMEAMASGVVVLSTVHSGIPELITDGESGFLVPEKDS
GAISRKIVEISKNQNLNIIRKNARCKVDDEFNARKLQTRLLEILKLKTV