Protein Info for MIT1002_01616 in Alteromonas macleodii MIT1002

Annotation: Lipid A core - O-antigen ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 466 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 37 to 56 (20 residues), see Phobius details amino acids 67 to 88 (22 residues), see Phobius details amino acids 128 to 147 (20 residues), see Phobius details amino acids 154 to 175 (22 residues), see Phobius details amino acids 202 to 220 (19 residues), see Phobius details amino acids 240 to 260 (21 residues), see Phobius details amino acids 266 to 285 (20 residues), see Phobius details amino acids 292 to 312 (21 residues), see Phobius details amino acids 378 to 399 (22 residues), see Phobius details amino acids 417 to 435 (19 residues), see Phobius details amino acids 441 to 458 (18 residues), see Phobius details PF04932: Wzy_C" amino acids 250 to 392 (143 residues), 68.8 bits, see alignment E=2.3e-23

Best Hits

KEGG orthology group: None (inferred from 82% identity to amc:MADE_02473)

Predicted SEED Role

"RbmD, similar to Lipid A core - O-antigen ligase and related enzymes"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (466 amino acids)

>MIT1002_01616 Lipid A core - O-antigen ligase (Alteromonas macleodii MIT1002)
MVNVLKTEKFLFGFLLFTLFWLPLSLGANRPWAWALMQMSLFSIGGTLVLLNTSLLHQLY
TKYRTFIILWVIFLAWQLINIVPLPFALVEAIRPERVSYLLSEQWGNQENVTSKWLSLSF
DVGQSDVTFFKSLAYCFLFFIALTLINSAKRLRYTLIVISAAGIFQAIYGALEVLSGIKY
SLVFKQPVSHIATGSYIYKNHYANFLMLCLSAAIGYLIASLHQDNTTTKRERLRRLVKFW
LSNKVLFRIGIIIMVIALVMSRSRMGNSAFFIAMTITATLGLIYFKPRQKSYITLFISML
IIDILLVSSFFGLKQVQQRLEQTNFAQESRDEVITDALPLLGEYGLIGTGGGTFYTVYPQ
FQSESIQHFYDHAHNEYLQFSIEFGVVGAFVLALLVLLCTKNALSAVRNRRHPLPRGTAF
ASIMATIGMALHSSVDFPLQAPANTAIFIVLLALGALSRDISMGRQ