Protein Info for MIT1002_01560 in Alteromonas macleodii MIT1002

Annotation: metal-dependent hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 PF13483: Lactamase_B_3" amino acids 76 to 284 (209 residues), 51.5 bits, see alignment E=1.8e-17 PF00753: Lactamase_B" amino acids 78 to 137 (60 residues), 24.2 bits, see alignment E=4.5e-09 PF12706: Lactamase_B_2" amino acids 89 to 284 (196 residues), 161.2 bits, see alignment E=3.9e-51

Best Hits

KEGG orthology group: None (inferred from 60% identity to sfr:Sfri_3864)

Predicted SEED Role

"Outer membrane protein romA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (340 amino acids)

>MIT1002_01560 metal-dependent hydrolase (Alteromonas macleodii MIT1002)
MTSFCGSSNTLAASAPQPEKFTNTHIEYKTTWRDMWKVTKAYFRDNRDAATPTFDIPVSA
LTPQMLDAVAEDSVIKLGHSTTLLKLAERYILIDPVFSERASPVQWMGPKRFHQAPISLE
DLPKLDAVIISHDHYDHLDKGSIEILKNKVDVFITPLKVGNHLRDWGVDANKVVELNWWQ
STKLSDIEIVATPSQHFSGRGLFDRDETLWASWVIKSANTNIFYSGDSGYFDGFKAIGEK
YGPFDLSMIETGAYNELWSDIHMLPEESLQAHIDIQASVMMPVHNSTFDLALHNWNEPLI
KITDLAGAKGVPTSIPIFGEVVPVKGAGEAPNKTWWLDER