Protein Info for MIT1002_01523 in Alteromonas macleodii MIT1002

Annotation: Ribosomal RNA large subunit methyltransferase M

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF18125: RlmM_FDX
  • amino acids 5 to 72 (68 residues), 63.4 bits, E=3.5e-21
• PF21239: RLMM_N
  • amino acids 86 to 168 (83 residues), 97.6 bits, E=5.4e-32
• PF01728: FtsJ
  • amino acids 191 to 285 (95 residues), 32.3 bits, E=1.4e-11

Best Hits

Swiss-Prot: 91% identical to RLMM_ALTMD: Ribosomal RNA large subunit methyltransferase M (rlmM) from Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)

KEGG orthology group: K06968, ribosomal RNA large subunit methyltransferase M [EC: 2.1.1.-] (inferred from 91% identity to amc:MADE_02563)

Predicted SEED Role

"LSU rRNA 2'-O-methyl-C2498 methyltransferase RlmM"

KEGG Metabolic Maps

• Alkaloid biosynthesis I
• Anthocyanin biosynthesis
• Benzoxazinone biosynthesis
• Biosynthesis of alkaloids derived from shikimate pathway
• Carotenoid biosynthesis - General
• Flavonoid biosynthesis
• Histidine metabolism
• Insect hormone biosynthesis
• Naphthalene and anthracene degradation
• Phenylpropanoid biosynthesis
• Porphyrin and chlorophyll metabolism
• Tryptophan metabolism
• Tyrosine metabolism
• Ubiquinone and menaquinone biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Protein Sequence (365 amino acids)

>MIT1002_01523 Ribosomal RNA large subunit methyltransferase M (Alteromonas macleodii MIT1002)
MPNTSILGYCRPGYENDTANELTSRYGEAQCYGYPVSKKNSGFVLYHLYDGSQLEQTITQ
FAVHDSIFPRQLVAVFATLNDIEKLDRVGQVLEALKEVEKPFQIFGAIDVEYPDTEEGKT
LAKFCRKFTVPLRQALRKAGWLTAKENLGKPKLHIFFESFEICHIGYTLPSHASGDHLGI
CRLKFPSDAPSRSTLKLEDALVNMLSDKQQAKVLRSGGRAVDLGACPGGWTYQLVKRGMY
VEAIDNGLVADSLMSTGLVEHHAADGFTYRPQFGRVDLLVCDMIEQPDRVAKLMGDWLVK
HWATHAIFNLKLPMKQRYETVVEAMTLLRGRLNALEDAFAVKVRHLYHDRDEVTVTIVRT
SKDEV