Protein Info for MIT1002_01432 in Alteromonas macleodii MIT1002

Annotation: t(6)A37 threonylcarbamoyladenosine biosynthesis protein RimN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 206 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family" amino acids 7 to 200 (194 residues), 230.4 bits, see alignment E=5.9e-73 PF01300: Sua5_yciO_yrdC" amino acids 22 to 198 (177 residues), 172.5 bits, see alignment E=3.2e-55

Best Hits

Swiss-Prot: 69% identical to YCIO_ECOLI: Uncharacterized protein YciO (yciO) from Escherichia coli (strain K12)

KEGG orthology group: K07566, putative translation factor (inferred from 97% identity to amc:MADE_02286)

Predicted SEED Role

"Hypothetical YciO protein, TsaC/YrdC paralog"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (206 amino acids)

>MIT1002_01432 t(6)A37 threonylcarbamoyladenosine biosynthesis protein RimN (Alteromonas macleodii MIT1002)
MSQFFYVHPDNPQKRLISQACELIREGAVVVYPTDSGYAIGCQMEDKKALEQLCRIRQID
KDHNFTLMCRDMSELSIYAKVDNTAFRQIKNNTPGRYTFVLKATREVPKRLQNPKRKTIG
IRVPDNAIALALLEELGEPLMSTSLILPGNTMAESDPDVIRDNLEKQVGLIIHGGYIGEQ
PTTVVDLSEDTPVIVRHGTGDPSPFE