Protein Info for MIT1002_01391 in Alteromonas macleodii MIT1002

Annotation: Ktr system potassium uptake protein B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 56 to 75 (20 residues), see Phobius details amino acids 87 to 111 (25 residues), see Phobius details amino acids 142 to 162 (21 residues), see Phobius details amino acids 170 to 190 (21 residues), see Phobius details amino acids 202 to 223 (22 residues), see Phobius details amino acids 235 to 258 (24 residues), see Phobius details amino acids 307 to 339 (33 residues), see Phobius details amino acids 360 to 380 (21 residues), see Phobius details amino acids 416 to 437 (22 residues), see Phobius details PF02386: TrkH" amino acids 42 to 437 (396 residues), 194.8 bits, see alignment E=1.1e-61 TIGR00933: potassium uptake protein, TrkH family" amino acids 44 to 426 (383 residues), 359.2 bits, see alignment E=1.5e-111

Best Hits

Swiss-Prot: 47% identical to KTRB_BACSU: Ktr system potassium uptake protein B (ktrB) from Bacillus subtilis (strain 168)

KEGG orthology group: K03498, trk system potassium uptake protein TrkH (inferred from 67% identity to vex:VEA_001289)

Predicted SEED Role

"Potassium uptake protein, integral membrane component, KtrB" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (454 amino acids)

>MIT1002_01391 Ktr system potassium uptake protein B (Alteromonas macleodii MIT1002)
MNRWDPGYRPIERSPKGINKIQVGPPLILSLSFVAVIFLGTVILKLPMMTHEPISWIQSL
FTSTSAVTVTGLVVVDTGSVFTTAGQAVIAVLIQLGGLGLMTFAIVTLIALGSKISFLQQ
SAVKEAFNQTDLSTLVSTAKSVLIFAFFVELVGFCILSAYWMQEKGVSEALFHAFFYTIS
AFNNAGFALSGDSLSAYVGDPIINITISALFIIGGLGFSVWIELHKKRRWQRISVYAKTM
ILGTLIVNVTAFLLIFVIESDNPATLANLDTQSALWASWFQAVTPRTAGFNTLDIASLED
PTTALMLLLMFIGGGSMSTASGIKLMTFIVLIIAAYNYIQRGAAPRLFGRTISNDTISKA
LALTMISIGITWIAIFLLLMSEKADFLDIVFEAVSALGTVGLSRGLTGELSNSGEWIIIL
LMYSGRLGPLTLAYFIASPRISRIKYPEAKLAIG