Protein Info for MIT1002_01373 in Alteromonas macleodii MIT1002

Annotation: Inner membrane protein YrbG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 322 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 36 to 62 (27 residues), see Phobius details amino acids 74 to 96 (23 residues), see Phobius details amino acids 107 to 120 (14 residues), see Phobius details amino acids 129 to 147 (19 residues), see Phobius details amino acids 174 to 196 (23 residues), see Phobius details amino acids 202 to 202 (1 residues), see Phobius details amino acids 205 to 227 (23 residues), see Phobius details amino acids 237 to 258 (22 residues), see Phobius details amino acids 269 to 291 (23 residues), see Phobius details amino acids 303 to 321 (19 residues), see Phobius details TIGR00367: K+-dependent Na+/Ca+ exchanger homolog" amino acids 3 to 312 (310 residues), 237.5 bits, see alignment E=9.5e-75 PF01699: Na_Ca_ex" amino acids 6 to 144 (139 residues), 98.9 bits, see alignment E=1.5e-32 amino acids 174 to 317 (144 residues), 131.4 bits, see alignment E=1.3e-42

Best Hits

KEGG orthology group: K07301, inner membrane protein (inferred from 88% identity to alt:ambt_11865)

Predicted SEED Role

"Inner membrane protein YrbG, predicted calcium/sodium:proton antiporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (322 amino acids)

>MIT1002_01373 Inner membrane protein YrbG (Alteromonas macleodii MIT1002)
MLLASLAILIGLPVLLWSAGKFVGGAASVANHFGVSPLLIGMLIIGFGTSAPEIIVSIFA
AIQGNSGIALGNAYGSNIANILLILGLTAIISPIAVKSEIIKKELPVLLGITFFAAWQVW
DLNISKDDAFSLLGLFVLLLSWSIYHGMKGDKDALADEYDEEINSNEGTVKTHVMWLIAG
LLLLVASSRMLVWGAVEVATFFGVSDTIIGLTVIAIGTSLPELASSLMAVKKGEHDLAIG
NVIGSNMFNTLAVVGIAGTIQPMTVGSEFLYRDVMVMFASTIALFIFCIGIKRQGRLNRL
EGGAFVLAYAAYTYWLIQAAFI