Protein Info for MIT1002_01275 in Alteromonas macleodii MIT1002

Annotation: Proline permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 501 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 44 to 61 (18 residues), see Phobius details amino acids 67 to 91 (25 residues), see Phobius details amino acids 123 to 142 (20 residues), see Phobius details amino acids 162 to 182 (21 residues), see Phobius details amino acids 192 to 215 (24 residues), see Phobius details amino acids 237 to 259 (23 residues), see Phobius details amino acids 280 to 301 (22 residues), see Phobius details amino acids 315 to 339 (25 residues), see Phobius details amino acids 371 to 391 (21 residues), see Phobius details amino acids 397 to 420 (24 residues), see Phobius details amino acids 429 to 447 (19 residues), see Phobius details amino acids 459 to 477 (19 residues), see Phobius details TIGR02121: sodium/proline symporter" amino acids 5 to 496 (492 residues), 686.9 bits, see alignment E=1.6e-210 PF00474: SSF" amino acids 34 to 437 (404 residues), 341.5 bits, see alignment E=3.4e-106 TIGR00813: transporter, solute:sodium symporter (SSS) family" amino acids 34 to 437 (404 residues), 300.2 bits, see alignment E=2.6e-93

Best Hits

Swiss-Prot: 58% identical to OPUE_BACSU: Osmoregulated proline transporter OpuE (opuE) from Bacillus subtilis (strain 168)

KEGG orthology group: K03307, solute:Na+ symporter, SSS family (inferred from 96% identity to amc:MADE_02712)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (501 amino acids)

>MIT1002_01275 Proline permease (Alteromonas macleodii MIT1002)
MATGTIISLGLYFVVMLGIGLFAYRQTDTNVEGYMLGGRQLGPAVTALSAGASDMSGWML
MGLPGAMYVSGLSAGWIAVGLTLGALANYMLVAPRLRVYTEVANNSITLPDYFENRFADN
TRLLRVIASVVIVVFFTLYTSSGVVAGGKLFETSFGLTYETGLYVTAGVVVAYTLVGGFM
AVSMTDFVQGCIMFVSLIMVPAVVISELGGIGASIDALDTINPALFDAFMDASTNEALSV
IGIVSLMSWGLGYFGQPHIIVRFMAIRSVKDIPTARNIGMSWMIVSIIGALMTGLFGLAY
ITGNGNEIDPETVFIYLSQILFHPLIGGFLLAAILAAIMSTISSQLLVTSSSLTSDFYQA
FLRRDASDGELVIAGRVSVVVVALVAIYLAYDRDSTILTLVSNAWAGFGAAFGPLVLFSL
FKREMTRRAALGGMIVGAVTVLLWIYLPIEIGGQKLGDWMYEIVPGFILSSLTIMILSKS
GSPREGVVDTFDAFQTKLTER