Protein Info for MIT1002_01267 in Alteromonas macleodii MIT1002

Annotation: Bacterial leucyl aminopeptidase precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 555 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF04389: Peptidase_M28" amino acids 312 to 526 (215 residues), 158.6 bits, see alignment E=8e-51

Best Hits

KEGG orthology group: None (inferred from 93% identity to amc:MADE_02720)

Predicted SEED Role

"Peptidase M28"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (555 amino acids)

>MIT1002_01267 Bacterial leucyl aminopeptidase precursor (Alteromonas macleodii MIT1002)
MKKMFLPLLVPTLLGVSACTPNNDSASQDQSAKKEMPVASNFDSVYNNISDADIREPLKV
LSSDEFEGRLPTTEGEKKTIEYLVSEFTKAGLKPGNGDSFLQKVALMEITADPDMTMTIG
DNNFAYKEQMVASSKREQSSVSLEDSELVFVGYGVNAPEYDWNDYEGLDVEGKTVVMLIN
DPGFENPESGKFQGTTMTYYGRWSYKYEEASRQGAAGAIIVHETAPASYGWSVVANSWSG
PQYGLVSADKGASRVAVEGWLTLDAAKKVFADAGLDFDQEKANAMQGPYNKAMDIKASVT
VNNTFKKSESNNVIATLPGEEFPDEHIIYTAHWDHLGKDESKEGDQIYNGAHDNATGTAA
ILAMAKAYSELTPAPKRSVSFLVVTAEEQGLLGSKYYASNPVIPIENTVANINMDAMNVL
GKTKNVAVVGMGKSEMEDYLEAAAAKQGRTLTQEDRPEAGYYYRSDHFSFAKQGVPALYA
EGGNEPADEETAKYRKRMNVIVTGCYHQVCDQYRDDWDLSGIVQDTQMLFDVGVGVANAE
AWPKWNEASEFQRQN