Protein Info for MIT1002_01230 in Alteromonas macleodii MIT1002

Annotation: putative 3-phenylpropionic acid transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 transmembrane" amino acids 21 to 46 (26 residues), see Phobius details amino acids 58 to 79 (22 residues), see Phobius details amino acids 88 to 107 (20 residues), see Phobius details amino acids 113 to 131 (19 residues), see Phobius details amino acids 151 to 171 (21 residues), see Phobius details amino acids 177 to 196 (20 residues), see Phobius details amino acids 219 to 242 (24 residues), see Phobius details amino acids 254 to 272 (19 residues), see Phobius details amino acids 279 to 299 (21 residues), see Phobius details amino acids 306 to 331 (26 residues), see Phobius details amino acids 344 to 363 (20 residues), see Phobius details amino acids 376 to 394 (19 residues), see Phobius details PF03825: Nuc_H_symport" amino acids 24 to 396 (373 residues), 76.8 bits, see alignment E=2.7e-25 PF12832: MFS_1_like" amino acids 25 to 377 (353 residues), 304.9 bits, see alignment E=1.3e-94 PF07690: MFS_1" amino acids 26 to 359 (334 residues), 64.6 bits, see alignment E=1.2e-21

Best Hits

KEGG orthology group: K05820, MFS transporter, PPP family, 3-phenylpropionic acid transporter (inferred from 93% identity to amc:MADE_02754)

Predicted SEED Role

"Nucleoside:H+ symporter:Major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (405 amino acids)

>MIT1002_01230 putative 3-phenylpropionic acid transporter (Alteromonas macleodii MIT1002)
MSPNGLNDAKSTSASPASSKTGLFILAITYWLYFGQLGVLVPYLGIFLDGRGFSSAEIGE
LFAVITLARILGPGLWAGVADKTGNAIGVMRLGCLLTVLTFSSVFYFTSFWGLTLAFGLM
MMFWTAVLPQLEVITMNTVAKTNATYGQVRLWGSVGFICLTVGVGKALDIFSTDTPVHAS
IGVLALLFISTLFIRAPKEAAPETSTAGSIWKYAKQKPFAIFIFASACLQISFGAYYGFF
ALYMRDLDYSGQQTGIFIALGVLAEVGIFLIARRLISQFGVWNLLFVSIALTGLRWYVMA
AFADTFMVIVLSQLIHALSFGLTHAVSVHFIHQFLPKAYQSRGQAVYISIAFGLGGAFGN
YMAGQQWQQGTNAYETFVTAAVFAAIGALSLLLCSRKEMESAKAA