Protein Info for MIT1002_01150 in Alteromonas macleodii MIT1002

Annotation: Leucine-responsive regulatory protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 155 PF13404: HTH_AsnC-type" amino acids 3 to 44 (42 residues), 63 bits, see alignment E=2.7e-21 PF13412: HTH_24" amino acids 3 to 49 (47 residues), 67.2 bits, see alignment E=1.1e-22 PF01037: AsnC_trans_reg" amino acids 66 to 149 (84 residues), 88 bits, see alignment E=4.5e-29

Best Hits

Swiss-Prot: 43% identical to GRP_ZYMMA: Glutamate uptake regulatory protein (grp) from Zymomonas mobilis subsp. mobilis (strain ATCC 10988 / DSM 424 / LMG 404 / NCIMB 8938 / NRRL B-806 / ZM1)

KEGG orthology group: K05800, Lrp/AsnC family transcriptional regulator (inferred from 97% identity to alt:ambt_12990)

Predicted SEED Role

"Transcriptional regulator, AsnC family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (155 amino acids)

>MIT1002_01150 Leucine-responsive regulatory protein (Alteromonas macleodii MIT1002)
MKLDKFDREILRVLQQDATVSMADLSQRVGLSHTPCWRRVKRMEADGIILGKVTLLNSKK
LNLGVSVFIYVTLKNHDGDSLTDFENAVQNIDEIVECHTTSGEKDYLLKVIVESIEEYEF
LLKTKLTHLPLVDHLSSTFALKQVKNTTELPIKRQ