Protein Info for MIT1002_01013 in Alteromonas macleodii MIT1002

Annotation: Cationic 19 kDa outer membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 171 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF03938: OmpH" amino acids 28 to 166 (139 residues), 88.3 bits, see alignment E=2.9e-29

Best Hits

Swiss-Prot: 40% identical to SKP_YERPE: Chaperone protein Skp (skp) from Yersinia pestis

KEGG orthology group: K06142, outer membrane protein (inferred from 99% identity to amc:MADE_01382)

MetaCyc: 34% identical to periplasmic chaperone Skp (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Outer membrane chaperone Skp (OmpH) precursor @ Outer membrane protein H precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (171 amino acids)

>MIT1002_01013 Cationic 19 kDa outer membrane protein (Alteromonas macleodii MIT1002)
MKQLVKHIVAGAMLGSALVSTSVMAEQKVAVVDVQGIFQAMPQAAEIQNAIQAEFKDQLE
EVNQLQRDGQFYAERLQRDAATMSDAEKKELEQKILSVREELAKKGQPLQQNIQRRSNEE
RNKLLGLIKQAIDSVAAKQGYDLVLNAGAVAFAKEEHDLSEQVLQQVSKTN