Protein Info for MIT1002_00974 in Alteromonas macleodii MIT1002

Annotation: Polysialic acid transport ATP-binding protein KpsT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 PF00005: ABC_tran" amino acids 22 to 152 (131 residues), 66 bits, see alignment E=2.8e-22

Best Hits

Swiss-Prot: 46% identical to KPST5_ECOLX: Polysialic acid transport ATP-binding protein KpsT (kpsT) from Escherichia coli

KEGG orthology group: K09689, capsular polysaccharide transport system ATP-binding protein (inferred from 98% identity to amc:MADE_03060)

Predicted SEED Role

"Capsular polysaccharide ABC transporter, ATP-binding protein KpsT" in subsystem Capsular Polysaccharide (CPS) of Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (224 amino acids)

>MIT1002_00974 Polysialic acid transport ATP-binding protein KpsT (Alteromonas macleodii MIT1002)
MIRIENLTKSYPSKMGPQYIFKNLNFDFPTENNVAILGKNGAGKSTLFRMLAKSEYPDRG
RVLTNKSMSWPVALQTGVHPQMTGRENTRFVGRINNVKSLPEYEERVQEFAELGARFDLP
VRTYSSGMRAKLVFACCMNINFDIYLIDEATSVGDPLFRKKARLSLKEKSEQAGVIMVSH
ELDQIREFCTSAVIIDEGKLTYYHDLEEGIDVYTQDADNKKSLK