Protein Info for MIT1002_00903 in Alteromonas macleodii MIT1002

Annotation: putative HTH-type transcriptional regulator YurK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 274 PF00392: GntR" amino acids 5 to 67 (63 residues), 64.9 bits, see alignment E=4.1e-22 PF07702: UTRA" amino acids 88 to 209 (122 residues), 103.9 bits, see alignment E=6.8e-34

Best Hits

Predicted SEED Role

"Histidine utilization repressor" in subsystem Histidine Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (274 amino acids)

>MIT1002_00903 putative HTH-type transcriptional regulator YurK (Alteromonas macleodii MIT1002)
MQPRYRVIKTAILDAIESGEMKPGSQVPSENQLAQQHRVSRMTARRALSEMVDEGILMRS
QGIGTFVSDSRPMSSMLEIKSIRDEIEQRGHRYTNEILVLETSPASDAIAQRLGIDVGEP
VFHSIIVHCENNLPVQYEDRWVNPAWINDYLDKDFKAQTANFYLNQVAPLSQADHSVEAV
VVEKDIAQALLIKPKEPCLKITRRTFSRVPSAITSDESNIGEPSTANAQLGNGLKATSDT
SVNNSPKASSSAVVSHAVLYHPGSRYRLGGHLEF