Protein Info for MIT1002_00854 in Alteromonas macleodii MIT1002

Annotation: aromatic amino acid exporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 36 to 53 (18 residues), see Phobius details amino acids 64 to 86 (23 residues), see Phobius details amino acids 93 to 117 (25 residues), see Phobius details amino acids 124 to 143 (20 residues), see Phobius details amino acids 158 to 179 (22 residues), see Phobius details amino acids 191 to 210 (20 residues), see Phobius details amino acids 219 to 240 (22 residues), see Phobius details amino acids 252 to 272 (21 residues), see Phobius details amino acids 278 to 299 (22 residues), see Phobius details PF00892: EamA" amino acids 8 to 140 (133 residues), 45 bits, see alignment E=6.7e-16 amino acids 160 to 292 (133 residues), 69 bits, see alignment E=2.7e-23

Best Hits

KEGG orthology group: None (inferred from 75% identity to amc:MADE_03168)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (310 amino acids)

>MIT1002_00854 aromatic amino acid exporter (Alteromonas macleodii MIT1002)
MNTSDVVKGVLAIVIASFLWGTTGTAAQFAPEISPLAIGAFAMGIGGVLLCVSARKSLVK
DAPILFSTPLTFLFGSACVAIYPLAFYSSMRLSGVAIGTVVSIASAPLFAALLEYFLSKK
PVSLKWFISFVFGAFGIGMLAMGKAHDSMALSASKDDQVFGVILGLIAGLTYAGYSWAAK
QHIDAGANSKSAMAGLFGCAAVALLPSLWFTGQNFFANTIHISVSLYMAVVPMFLGYLLF
GYGLRTTEASKATLITLIEPLVATLFAIFLIGEVFKPVGWVGMTLVCLCLLIQSIKFPFA
LKRYGKKATA