Protein Info for MIT1002_00816 in Alteromonas macleodii MIT1002

Annotation: Cytochrome c1 precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 244 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 217 to 235 (19 residues), see Phobius details PF02167: Cytochrom_C1" amino acids 30 to 242 (213 residues), 72.7 bits, see alignment E=3.7e-24

Best Hits

KEGG orthology group: K00413, ubiquinol-cytochrome c reductase cytochrome c1 subunit [EC: 1.10.2.2] (inferred from 92% identity to alt:ambt_14670)

Predicted SEED Role

"ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit" in subsystem Ubiquinone Menaquinone-cytochrome c reductase complexes

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.10.2.2

Use Curated BLAST to search for 1.10.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (244 amino acids)

>MIT1002_00816 Cytochrome c1 precursor (Alteromonas macleodii MIT1002)
MKKMMCFLAFFLPGVAFAAGGNVHLDEAPIDLTDKASLQRGAQLFMNYCLGCHSMKYQRY
QRSFQDLGIPDELGQEYLQFTGDKVSDYITRAMPEEAAAGWFGAAPPDLTLVARVRGEDW
IYTYLRSFYVDESRPFGVNNTVFPEVGMPHVLQPLQGTPTRTYEEQMVDGEMVKRYVGIK
SDGTGAMSPDEYDQAVADIVNFLEYTGEPAKLESHKIGKWVLIFIAVLFVFVYLLKKEYW
REVH