Protein Info for MIT1002_00810 in Alteromonas macleodii MIT1002

Annotation: Transcriptional regulatory protein BasR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 221 PF00072: Response_reg" amino acids 3 to 113 (111 residues), 97.1 bits, see alignment E=7.3e-32 PF00486: Trans_reg_C" amino acids 146 to 215 (70 residues), 75.5 bits, see alignment E=2.8e-25

Best Hits

Swiss-Prot: 44% identical to PMRA_PECPM: Transcriptional regulatory protein PmrA (pmrA) from Pectobacterium parmentieri

KEGG orthology group: K02483, two-component system, OmpR family, response regulator (inferred from 85% identity to amc:MADE_03384)

Predicted SEED Role

"response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (221 amino acids)

>MIT1002_00810 Transcriptional regulatory protein BasR (Alteromonas macleodii MIT1002)
MRVLLVEDDRPLSGALALSLKNANFTVDCVYSGADALATLRAGQSDIVILDLGLPDTDGL
DVLKSIRKKNATLPVLILTARDKTLDKISGLDAGADDYLPKPFEIEELLARIRVLERRLS
TASHSIVSVKNVSLDTAHYTLTIDNQNVHLPRRELMLLKALIENAGRILSKDQLENKLYE
WGEEVASNTIEVHVSNLRKKMPPEFIKTIRGVGYCISKSGE