Protein Info for MIT1002_00802 in Alteromonas macleodii MIT1002

Annotation: Thermostable hemolysin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 247 transmembrane" amino acids 123 to 142 (20 residues), see Phobius details amino acids 149 to 171 (23 residues), see Phobius details PF12261: T_hemolysin" amino acids 34 to 204 (171 residues), 141 bits, see alignment E=1.8e-45

Best Hits

KEGG orthology group: None (inferred from 97% identity to amc:MADE_03392)

Predicted SEED Role

"Thermostable hemolysin delta-VPH"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (247 amino acids)

>MIT1002_00802 Thermostable hemolysin (Alteromonas macleodii MIT1002)
MSHVLASVPTQVASQQSAIVSKEKPAITFIAAKHGHNARRRIEAFIASGFKARYNARVTS
FMPMLFALDAKGVKAAAGARFATYDGQYNSLFIEQYLNTSVETALTLQGITVNRAHIAEV
GNLFSSASRYTLPLLFALFFVLKRCGSKYLVFSATSQLTSLLMGAGIQLLPLVKADASKL
KGNSDDWGTYYDTAPQVTALSLHHVTQHIIGCPELNAHYQRAIELISANVDALTQNICTK
KETAYVA