Protein Info for MIT1002_00716 in Alteromonas macleodii MIT1002

Annotation: Outer membrane cobalamin translocator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF07715: Plug" amino acids 56 to 162 (107 residues), 87.1 bits, see alignment E=1.7e-28 PF00593: TonB_dep_Rec" amino acids 222 to 624 (403 residues), 153 bits, see alignment E=3.7e-48 PF14905: OMP_b-brl_3" amino acids 448 to 630 (183 residues), 34.5 bits, see alignment E=2e-12

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 86% identity to amc:MADE_03647)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (650 amino acids)

>MIT1002_00716 Outer membrane cobalamin translocator (Alteromonas macleodii MIT1002)
MERIKDNIKTMRTHFTKAALSAAVISCISTATFAQNSDQDIETLTVTGTRLPISLTKLPG
SVSVLTESDIKASGALQLTDLIRGLPGVSLSQSGSPGGLTELRVRGGETNHLLVLIDGVV
ANDVGQGSLVDLAHLTSTNVVRIELLRGPQSARWGSGAIGGVLSITTKSGQFADNASHVD
FSAGVGTQGTLQGSMNARSQSDNVGVSAYASYIRTDGDNVSRVGNEDDGYDNMTAGININ
YAATSEHKLIANLRTVQYENDYDGTDFVTTGLPADSDNVTDGSQISAKLRWEFAPENTGY
RAALSAHYRKDDNDNTESGVDTGGTTGERIELSWTGFYTMDNWDFAGGVEYLQRLFTQRG
PIAFGDPNQKQHDNTYSVFAETNGQLTESLTATLSARFDNNSEFDNAVSYRGGLTWQLNE
YYAVFTSYGKAVKTPTFTERFGYFPASFIGNPNLEPETSEEWEVGVKANWKSLSAQISAY
TTDLEDEINGFVYVPDLGAYSADNIDGDSSREGIDLELSWDSGYGDFTAAYSYLDAEQTD
NGITTTELRRARHQGSLIYNTDFGTQKFSFYTKLAYTGSHYDTFFPPYPEPSQTLALSAY
TLATINLGYQIDKQWQVSLKVDNVFDNDYEDIVGYAGQERRALLSVNYSM