Protein Info for MIT1002_00707 in Alteromonas macleodii MIT1002

Annotation: Chemotaxis regulator BdlA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 PF13426: PAS_9" amino acids 35 to 125 (91 residues), 32.2 bits, see alignment E=2.6e-11 amino acids 158 to 252 (95 residues), 46.6 bits, see alignment E=9e-16 TIGR00229: PAS domain S-box protein" amino acids 35 to 131 (97 residues), 38.3 bits, see alignment E=6.6e-14 amino acids 152 to 263 (112 residues), 50.3 bits, see alignment E=1.3e-17 PF00989: PAS" amino acids 37 to 128 (92 residues), 22.7 bits, see alignment E=2e-08 amino acids 155 to 246 (92 residues), 34.7 bits, see alignment E=4.1e-12 PF08447: PAS_3" amino acids 47 to 127 (81 residues), 27.6 bits, see alignment E=7.1e-10 amino acids 166 to 252 (87 residues), 44.7 bits, see alignment E=3.3e-15 PF08448: PAS_4" amino acids 154 to 259 (106 residues), 37.1 bits, see alignment E=8.1e-13 PF00015: MCPsignal" amino acids 276 to 433 (158 residues), 135.4 bits, see alignment E=4.9e-43

Best Hits

Swiss-Prot: 39% identical to BDLA_PSEAE: Biofilm dispersion protein BdlA (bdlA) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 87% identity to amc:MADE_03655)

Predicted SEED Role

"methyl-accepting chemotaxis sensory transducer"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (438 amino acids)

>MIT1002_00707 Chemotaxis regulator BdlA (Alteromonas macleodii MIT1002)
MFFKNKELIAENQRLEKEMAAHETVKEELREEMLYIELNADGRISAINDLYTQATGFKIS
ELEGKSLESLMDPKSLKKSDVQDMLGAIKNHRHWHGAVRFNNAKGHEIWVRGIIQPIDDA
YGNVKCISFYMAEQTRNISYSNELRDMIAALHRSSAVIEFNLDGTIIKANENFLKGLGYK
LEQLVGKHHRIFCTEQEVNSEEYKQFWRGLAQGQLESGRYKRIDSRGNDVWLEASYNPIR
NEDGQLYKVVKFATVITEQMKREFAISEAANVAFNISQETGEQARKGNQVLDSTVKAMNE
LTKQMGNASEGIKDLDEQSQKVADLVKSISGIADQTNLLALNAAIEAARAGDQGRGFAVV
ADEVRQLASRTSSATEEIVNVVVENRKLTENAVQLIEAGQEKAREALEYSTQSGKAMSEI
QSGANEVVNAIGQFTKRL