Protein Info for MIT1002_00667 in Alteromonas macleodii MIT1002

Annotation: tetratricopeptide repeat protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 924 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details TIGR02917: putative PEP-CTERM system TPR-repeat lipoprotein" amino acids 15 to 902 (888 residues), 501.7 bits, see alignment E=1.8e-154 PF13432: TPR_16" amino acids 39 to 92 (54 residues), 19 bits, see alignment 1.3e-06 amino acids 791 to 838 (48 residues), 20.4 bits, see alignment 5.1e-07 PF13414: TPR_11" amino acids 42 to 79 (38 residues), 28.6 bits, see alignment (E = 7.7e-10) PF14559: TPR_19" amino acids 44 to 94 (51 residues), 31.6 bits, see alignment 1.4e-10 amino acids 182 to 236 (55 residues), 31.5 bits, see alignment 1.5e-10 PF13174: TPR_6" amino acids 204 to 235 (32 residues), 15.8 bits, see alignment (E = 1.5e-05)

Best Hits

KEGG orthology group: None (inferred from 87% identity to amc:MADE_03692)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (924 amino acids)

>MIT1002_00667 tetratricopeptide repeat protein (Alteromonas macleodii MIT1002)
MTKMKPNTLLKRTTLAVMLTSALLSGCSEKTMESHLADARNYASSQQIDAAIVEYKNAIQ
KAPDAAAPRFELGKLYLQQSNFSAAEKELNKAMELGHPVSQVIPLLSVAYQQSGAENALA
EVDYRAEGMSAVESAEVGFYKLQALMQLGKNEEAQTLLADLSTLDTSSVYKGLIDSYAFV
LDNDMDGALAATEKLREQAPTNKDVLQQLAKIYLQNGEPEKAAEVYGVYVSQFPDDVTSK
FAYAALLIEIRDLDNAQPIVDDLLVLNENHPLLNTFKGIIESANENYAKALEHLEIAVQN
GRSDQVVRLVAGFSAYQIQDFEAAQRHLTMVASSLPDNHPGLRMLADSMLQLGENDEALE
VLARVEGEQGVDAALFSKASYQLLREGNVIGAQQMVEKSEGVSTTAEDLSRLGVLQLSLN
DIDGLVNLEQAVEQAPESVTSQATLLRAYIATNQLEKAKSAAKEWHEQSPETAAPLIYLG
NIATAEGAYQEAAQYLDKASELEGAKNEVFYSRAKLLVAEGKNDNAISFVRAFIDKNPAD
VQALALWFALATEKGNAEDVIKYTQTQFNANKTNLNLRLLLARMYSLNSQLDKTVSLLSD
VEGNEASPQAFWNLKGQALIATNNVEAATAFFDRWLSFYPQDKNAVLGKLLIIDSQKQFD
QGLALTNKVLAKRPDAQLTLLKAYFHSRLGQAKPAWDIINSTADDVKALPFVRGVIARLH
LIDKAPEQAVEHAQAAYDATPNSDNALLLIAALEMSGKKAQAFTFLEKHVQAHSNDIPSA
MLLAERQIGKDRAAAIKTYEQVLTKTPDNFVVLNNLAYLAFEDKNLTRAEELAKKAVSLQ
RENADAVDTLAQIYVAKGDKAAALKLYEEVSARPIANDDVYLNHVSVLLELDKKALASRK
LASREFKSEAAKQRAESLKQQYGL