Protein Info for MIT1002_00638 in Alteromonas macleodii MIT1002

Annotation: Outer membrane protein OprM precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 480 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 12 to 477 (466 residues), 244.1 bits, see alignment E=1.4e-76 PF02321: OEP" amino acids 78 to 268 (191 residues), 80.7 bits, see alignment E=6.4e-27 amino acids 292 to 475 (184 residues), 66.8 bits, see alignment E=1.2e-22

Best Hits

Predicted SEED Role

"RND efflux system, outer membrane lipoprotein, NodT family" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (480 amino acids)

>MIT1002_00638 Outer membrane protein OprM precursor (Alteromonas macleodii MIT1002)
MGKIKLTVNSITLCILLSACTSTDDRALSESASSSTGNNVVWQSQAQQQESTQTLLLNSD
TTLTDVIDIKELPHLAGYIDEALSSNASLQQSLITLRKAQVAIDSAKADRNLNVDASFSA
SKSETTNSNASTSSSTSSNSISPSYSASMNVSWELDLWQKISDGISAANLDAASARASYQ
SARDSLVANVVRSYIDVLTQQQLLNIEQSRLTVLENNEAVILKRYSTGLGSLDDLDTART
SSANTRATIAQYENALLTAKRTLAVLLGRQNQSLNELNTQVSFPDVLLPLTTLPKQDLAR
RPDLQAAFYALKATEFEVDVAYKALLPSISLSASLSDNASTPSQALFTNPLWSLLGQMTA
PLFQGGALRAQVEDAKLTSANAWWQYRETLLTAVQETQNALDSETALSARISHTNVALAN
AERSVSTIEGQYRQGLADILDLLSVYDTRFNLQAQAVELHAQKLQNRIDLGLALGLGVSQ