Protein Info for MIT1002_00461 in Alteromonas macleodii MIT1002

Annotation: Catalase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00199: Catalase
  • amino acids 17 to 395 (379 residues), 587.7 bits, E=1.1e-180
• PF06628: Catalase-rel
  • amino acids 428 to 488 (61 residues), 68.3 bits, E=5.2e-23

Best Hits

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 96% identity to amc:MADE_00522)

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• ethanol degradation IV (3/3 steps found)
• superoxide radicals degradation (2/2 steps found)
• methanol oxidation to formaldehyde IV (1/2 steps found)

KEGG Metabolic Maps

• Methane metabolism
• Tryptophan metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.6

Protein Sequence (491 amino acids)

>MIT1002_00461 Catalase (Alteromonas macleodii MIT1002)
MSKCPFSGTAIKPTTLTSSNGAPVANDNQSRTAGPRGPVTFDNHYLFEKLAHFNRERIPE
RVVHARGSAAYGTFTLTKSLSDYTIADFLQKEGQKTDVFLRFSTVGGGQDSSDYARDPRG
FSVKFYTEQGNWDMVGNNTPVFFLRDGIKFPDFIHSQKKNPRTNLPDPQAVYEFWANNPQ
SLHQSTILMSDRGIPLSYRHVNGYSSHTLSFWNNAGERYWVKWHFKTNQGIKTLTSEEAA
KMPAYGAQQDLVESIDNGEFPSWTVNVQIMTEEEARNYHINPFDLTKVWPHSDFPLIEVG
QLELNRNVDNYFAETEQAAFAPSNLVPGIGASPDRMLQARLIGYQDAHRYRIGANYNQIP
VNAPRCPVHNYQRDGAFAGINPALAGSGANFYPNNRARVGEPAEAPEVQEPPMPLEQDAW
LDIYDNRDEDNYSQAGDLYRIMSEDQKHQLVNNIADGLSQATKDVQEAMFVQYDLADSDY
GERVRKAVANK