Protein Info for MIT1002_00401 in Alteromonas macleodii MIT1002

Annotation: Peptidyl-dipeptidase dcp

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 729 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF19310: TOP_N" amino acids 77 to 197 (121 residues), 37 bits, see alignment E=2.8e-13 PF01432: Peptidase_M3" amino acids 270 to 719 (450 residues), 345.8 bits, see alignment E=5.7e-107

Best Hits

KEGG orthology group: K01284, peptidyl-dipeptidase Dcp [EC: 3.4.15.5] (inferred from 97% identity to amc:MADE_00465)

Predicted SEED Role

"Dipeptidyl carboxypeptidase Dcp (EC 3.4.15.5)" in subsystem Protein degradation (EC 3.4.15.5)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.15.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (729 amino acids)

>MIT1002_00401 Peptidyl-dipeptidase dcp (Alteromonas macleodii MIT1002)
MGKFKSSLTAMAVVVALGACSEQKAPETTSTDVQNTATSQQAQFDNVLLQEFKGPYGGVP
AFDKMNLEDLKPALEKAMELNLKEIEAIANNEAPPTFENVIVEMERAGAELGRVFTYYGI
WSSNKSSPEFREIQAEMSPKLSAFFTQITQNEKLFERVKTVYESDELKSLTPEEQRITWM
TYNSFARNGATLDGEAKKRYAEINQELATLHTKFSNNVLADEENYVTYITEDQLDGLPAS
FVKAAKAAAESRGEEGKYAITNTRSSMDPFLTYSTNRELREKVWRTYYNRGDNADEFDNN
DIIKRILTLRDERVELLGYENYAQWRLEDRMAKNPENAMDLMMKVWPAAIARVEEEVADM
QAIADEEGADITIAPWDYRFYAEKVRQAKYDLDSNEVKQYLQLDKLREAMFYVAGRLFNF
NFTPVEEGKVPVFHEDVKVWEVTDKDSGEHIGLWYLDPFSRQGKRSGAWATTYRSYTTFD
GKKTVLSSNNSNFVKGADGEATLISWDDAETYFHEFGHALHFLASDVEYPSSHSGVRDYT
EFQSQLLERWLTTDEVINNYLVHHETGEPIPAELVEKIKKASTFNEGFKTTEYMASAIMD
LKYHTTDPSKIDPDTFEREELKKLGMPEEIVMRHRSPHFGHVFSGEGYAAAYYGYMWAEV
LTADAAEAFMEAPGGFYDKEVGDRLVKYLFAVRNAMDPAEAYRKFRGRDAKVDALMRDRG
FPIPKESKE