Protein Info for MIT1002_00187 in Alteromonas macleodii MIT1002

Annotation: Aldose 1-epimerase precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01263: Aldose_epim
  • amino acids 19 to 336 (318 residues), 267 bits, E=1.2e-83

Best Hits

KEGG orthology group: K01785, aldose 1-epimerase [EC: 5.1.3.3] (inferred from 76% identity to amc:MADE_00230)

Predicted SEED Role

"Aldose 1-epimerase (EC 5.1.3.3)" in subsystem Lactose and Galactose Uptake and Utilization or Maltose and Maltodextrin Utilization (EC 5.1.3.3)

MetaCyc Pathways

• D-galactose degradation I (Leloir pathway) (5/5 steps found)
• trehalose degradation VI (periplasmic) (2/2 steps found)

KEGG Metabolic Maps

• Glycolysis / Gluconeogenesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.3.3

Protein Sequence (339 amino acids)

>MIT1002_00187 Aldose 1-epimerase precursor (Alteromonas macleodii MIT1002)
MKINVSAFGEVEGEVINAFTLTNDNGMSVTLLNYGGIIKEIHFPNAEGESVSCVQTFETL
QDYIDDPSYRGAIVGRYANRIGHGSFALNGTEYTLDKNGGEHNLHGGLAGFHKKVWAASV
QETTDSVAVTFTLTSPDGEGGFPGTVNVEACYSLGQNNELSLVITANTDKETPLSFTQHA
YFTLSNDPQVGNTLLHIDADKVTDADSTLLPTGKLVEVANTPFDFTKPTAIKERAEQSNS
HPLFDRVGGYDHNYVLRDTPEHTPQATVKALDTGVAMSLFTNLPGLQFYTGGLKTDDQLG
ALCLEPQHFPDAPNKPEFPNCFVKPGETFKASMRYKFSA